E2F1 Gene - GeneCards | E2F1 Protein | E2F1 Antibody
2024年12月24日 · E2F1 (E2F Transcription Factor 1) is a Protein Coding gene. Diseases associated with E2F1 include Retinoblastoma and Squamous Cell Carcinoma. Among its …
E2F - Wikipedia
E2F is a group of genes that encodes a family of transcription factors (TF) in higher eukaryotes. Three of them are activators: E2F1, 2 and E2F3a. Six others act as repressors: E2F3b, E2F4 …
癌症中的E2F转录因子家族 - 知乎 - 知乎专栏
乳腺癌小鼠模型中，e2f1和e2f2调节是对血管生成、细胞外基质重塑和肿瘤细胞与内皮细胞之间的相互作用至关重要的一组基因表达。 因此，E2Fs失调不仅通过调节细胞周期和基因组稳定性 …
E2F1 - Wikipedia
1869 13555 Ensembl ENSG00000101412 ENSMUSG00000027490 UniProt Q01094 Q61501 RefSeq (mRNA) NM_005225 NM_007891 NM_001291105 RefSeq (protein) NP_005216 …
E2F Transcription Factor 1 Regulates Cellular and
2014年12月5日 · We mapped the interaction between E2F1 and FOXO3 to a region including the DNA binding domain of E2F1 and the C-terminal transcription-activation domain of FOXO3. …
Posttranslational modifications of E2F family members in the ...
2024年9月1日 · The E2F transcription factor family, whose members are encoded by the E2F1-E2F8 genes, plays pivotal roles in the cell cycle, apoptosis, metabolism, stemness, …
基于生物信息学分析构建转录因子 E2F1 调控微RNA及其靶向基因 …
利用GTRD，在transcription factor target genes中选择物种（organism）：Human；转录因子（transcription factor）：E2F1 QO1094；转录因子结合位点（TF binding site …
Structural insights into the DNA-binding specificity of E2F ... - Nature
2015年12月3日 · Our results represent the first crystal structure of an E2F protein with two DBDs, and reveal the mechanism by which atypical E2Fs can repress canonical E2F target genes …
E2F1 and E2F2 prevent replicative stress and subsequent p53
2015年2月6日 · We show that inactivation of E2F1 and E2F2 results in accumulation of DNA replication mediators, activation of the DNA damage response (DDR) and induction of p53 …
The genetics of the E2F family of transcription factors: shared ...
2002年6月21日 · The elimination of immature and mature autoreactive T cells via apoptosis is an essential mechanism to prevent autoimmunity. E2F1 has been shown to play a critical role in …