EA-2192 is an extremely potent acetylcholinesterase inhibitor. It is almost as toxic as VX itself. [3] EA-2192 behaves similar to aged soman as it is the dealkylated form of VX and cannot be reversed with common oxime reactivators. EA-2192 from VX

EA-2192于1954年完成初步评价被送往英国军方进行更为深入的研究与评估，很快就为军队列入制式装备，并在后来受到多国重点关注与研究，属于第三代化学战剂。 OP在美国化学部队中的正式编号为EA-2192，因一直未有正式名称而常以其代号VX作为其称呼。 EA-2192纯品为无色无嗅的油状液体，外观类似于机油，蒸发速度介于轻质机械油与机油之间，工业品为微黄色至棕黄色的油状液体，有硫醇气味，毒剂含有杂质或贮存过久时也会产生硫醇气味并略显黄色，此点有助于判 …

EA-2192是VX神经毒剂的降解产物。 [1] [2] 它是极易溶于水且剧毒的白色固体。它是很强的 乙酰胆碱酯酶抑制剂 （ 英语 ： acetylcholinesterase inhibitor ） ，毒性可和VX神经毒剂相比。 [3]

EA-2192 is only about 2-3 times less toxic than VX. However, EA-2192 Is a nonvolatile Ionic compound which cannot be detected by traditional methods used for VX, including GO/MS analysis or AgF conversion to the G analog. Analytical methods were needed that were capable of determining the amount of EA-2192 in decontamination solutions

2024年3月1日 · EA-2192 is the very toxic degradation product of VX with an intravenous LD 50 of 18.3 µg/kg in rat compared to 10.8 µg/kg for VX (Reiter et al., 2011).

2011年9月15日 · After intravenous and percutaneous administration of a supralethal doses of VX in anaesthetised swine both VX and EA-2192 could be quantified over 540 min following exposure. This study is the first to verify the in vivo formation of the toxic metabolite EA-2192 after poisoning with the nerve agent VX.

EA-2192 is an intermediate form during the neutralization reaction which further reacts to form MPA. EA-2192 is a nerve toxin. Analysis for VX and EA-2192 is carried out on a homogenized sample (including both aqueous and organic layers) of the hydrolysate.

2012年3月16日 · The analytically challenging, zwitterionic S-2-(N,N-diisopropylaminoethyl) methylphosphonothiolate (EA-2192), a highly toxic degradation marker of the nerve agent VX, has been reported to resist trimethylsilylation or to result in an unacceptably high limit of detection in GC-MS analysis.

2012年3月16日 · The analytically challenging, zwitterionic S-2-(N,N-diisopropylaminoethyl) methylphosphonothiolate (EA-2192), a highly toxic degradation marker of the nerve agent VX, has been reported to resist trimethylsilylation or to result in an unacceptably high limit of detection in GC–MS analysis.

The former product, known as EA-2192, retains much of the neurotoxicity of the intact agent, and hence presence of this compound is an ongoing source of concern. In fact, the state of Utah requires measurement of EA-2192 to ensure detoxification to closure standards (see Chapter 5 ).