
Epidermal growth factor-stimulated Akt phosphorylation requires ...
2015年10月1日 · Epidermal growth factor (EGF) binding to its receptor (EGFR) activates several signaling intermediates, including Akt, leading to control of cell survival and metabolism. …
EGF-activated PI3K/Akt signalling coordinates leucine uptake …
2019年7月25日 · Growth factor-activated PI3K/Akt signalling pathway regulates leucine transport through LAT3 in prostate cancer cell lines. These data support a direct link between growth …
Regulation of EGF-stimulated activation of the PI-3K/AKT
2022年11月29日 · The phosphoinositide-3 kinase (PI-3K)/AKT cell survival pathway is an important pathway activated by EGFR signaling. Here we show, that in addition to previously …
Epidermal Growth Factor Receptor Cell Proliferation Signaling …
Epidermal growth factor receptor (EGFR) signaling pathways leading to G1/S cell cycle progression activated by EGF activation. Depicted are the RAS-RAF-MEK-ERK MAPK and …
AKT Facilitates EGFR Trafficking and Degradation by …
We investigated the role of AKT in EGFR trafficking and discovered a negative feedback loop in which EGF-mediated activation of AKT promotes EGFR progression through the early …
Growth hormone modulation of EGF-induced PI3K-Akt pathway …
Considering GH modulation of EGFR expression and activation, the relevance of the PI3K-Akt signaling in cell survival and in the pathogenesis of cancer, as well as the implication of GH …
BDNF 通过 PI3K/Akt 通路促进 EGF 诱导的人类胎儿神经干细胞/祖 …
bdnf 对 egf 诱导的 nspc 增殖和迁移的增强作用被 pi3k 抑制剂 ly294002 消除。这些发现表明 bdnf 通过 pi3k/akt 途径促进 egf 诱导的 nspc 增殖和迁移,不仅为 egf 诱导的神经发生的机制提供 …
Regulation of EGF-stimulated activation of the PI-3K/AKT pathway …
We propose a positive feedback mechanism in which exocytosis regulates a key signaling pathway downstream of EGFR. The phosphoinositide-3 kinase (PI-3K)/AKT cell survival …
Epidermal growth factor–stimulated Akt phosphorylation requires ...
Epidermal growth factor (EGF) binding to its receptor (EGFR) activates several signaling intermediates, including Akt, leading to control of cell survival and metabolism.
Akt-elicited phosphorylation of Acapin steers cell migration
5 天之前 · In cells, EGF stimulation elicits Akt signaling, which recruits Acapin to the lamellipodium membrane via phosphorylation of Acapin at its Ser247 residue and enhances the binding of …