2015年10月1日 · Epidermal growth factor (EGF) binding to its receptor (EGFR) activates several signaling intermediates, including Akt, leading to control of cell survival and metabolism. …

2019年7月25日 · Growth factor-activated PI3K/Akt signalling pathway regulates leucine transport through LAT3 in prostate cancer cell lines. These data support a direct link between growth …

2022年11月29日 · The phosphoinositide-3 kinase (PI-3K)/AKT cell survival pathway is an important pathway activated by EGFR signaling. Here we show, that in addition to previously …

Epidermal growth factor receptor (EGFR) signaling pathways leading to G1/S cell cycle progression activated by EGF activation. Depicted are the RAS-RAF-MEK-ERK MAPK and …

We investigated the role of AKT in EGFR trafficking and discovered a negative feedback loop in which EGF-mediated activation of AKT promotes EGFR progression through the early …

Considering GH modulation of EGFR expression and activation, the relevance of the PI3K-Akt signaling in cell survival and in the pathogenesis of cancer, as well as the implication of GH …

bdnf 对 egf 诱导的 nspc 增殖和迁移的增强作用被 pi3k 抑制剂 ly294002 消除。这些发现表明 bdnf 通过 pi3k/akt 途径促进 egf 诱导的 nspc 增殖和迁移，不仅为 egf 诱导的神经发生的机制提供 …

We propose a positive feedback mechanism in which exocytosis regulates a key signaling pathway downstream of EGFR. The phosphoinositide-3 kinase (PI-3K)/AKT cell survival …

Epidermal growth factor (EGF) binding to its receptor (EGFR) activates several signaling intermediates, including Akt, leading to control of cell survival and metabolism.

5 天之前 · In cells, EGF stimulation elicits Akt signaling, which recruits Acapin to the lamellipodium membrane via phosphorylation of Acapin at its Ser247 residue and enhances the binding of …