Occludin靶点介绍及实验小贴士| Abcam中文官网
细胞旁转运（Paracellular transport）是指分子在相邻上皮细胞之间运输，而紧密连接可调节细胞旁路渗透性并维持细胞极性。 Occludin当细胞缺乏紧密连接时，可以诱导粘附。 Occludin可 …
Epithelial-mesenchymal transition (EMT) signature is inversely ...
2018年2月13日 · Epithelial-mesenchymal transition (EMT) is able to drive metastasis during progression of multiple cancer types, including non-small cell lung cancer (NSCLC).
Occludin Is Involved in Adhesion, Apoptosis, Differentiation …
2013年2月4日 · Downregulation of Ocln has been described to be involved in EMT. Especially in the context of TGFβ induced EMT recent studies in simple epithelial cells indicate high …
上皮间质转化(EMT)4种标志物介绍 - 知乎 - 知乎专栏
激活上皮间质转化（EMT）是癌细胞转移的关键过程，在此过程中，上皮细胞获得间充质细胞的特征，细胞运动性和迁移能力增强。EMT 的特征在于上皮细胞标志物（例如cytokeratins和 E …
表观遗传学第四讲——EMT过程中的表观遗传修饰 - 知乎
上皮-间充质转化(emt)是一种生物学过程，非运动的、极化的上皮细胞经历一系列的生化改变，成为具有侵袭能力、抗凋亡和细胞外基质(ecm)成分生物合成改变的运动的、非极化的间充质细 …
上皮细胞-间充质转化(EMT)标志物—Antibody IHC/WB Panel
上皮细胞-间充质转化(emt)，是指上皮细胞通过特定程序转化为具有间质表型细胞的生物学过程。 在胚胎发育、慢性炎症、组织重建、癌症转移和多种纤维化疾病中发挥了重要作用，其主要的 …
Epithelial-mesenchymal Transition (EMT) and the Effect of …
2024年5月22日 · The induction of EMT in ARPE-19 cells increased the expression of mesenchymal markers ACTA2/α-SMA and fibronectin and reduced the expression of epithelial …
Constructing a doxycycline-inducible system for an epithelial-to ...
2024年12月9日 · By monitoring the changes in epithelial and mesenchymal markers at different induction time points, we examined the EMT process in both polyclonal and monoclonal …
Occludin protects secretory cells from ER stress by facilitating ... - PNAS
2020年2月12日 · Ocln mutant milk-producing cells exhibit defective protein secretion and augmented endoplasmic reticulum stress and unfolded protein response, ultimately leading to …
Influence of Ocln on epidermal differentiation and EMT markers ...
Suppression of Ocln is a common feature of epithelial-mesenchymal transition (EMT) in tumors derived from epithelial cells and is vital in metastasis in cancer [21].