The role of proton pump inhibitor (PPI) therapy in eosinophilic esophagitis (EoE) has become increasingly perplexing over the last decade despite numerous advances in our understanding …

Proton-pump inhibitors (PPIs) are the most administered first-line treatment for eosinophilic esophagitis (EoE). However, only around half of EoE patients respond histologically to a …

2025年2月5日 · When the gastrointestinal eosinophilia is limited to the esophagus and is accompanied by characteristic symptoms, it is termed eosinophilic esophagitis (EoE). EoE is …

EoE and PPI-REE share similar clinical, endoscopic, histologic, immunologic, and molecular features before PPI treatment, suggesting that distinguishing these entities with a medication …

2024年7月2日 · Your health care provider will consider both your symptoms and test results to diagnose eosinophilic esophagitis. This will include determining whether you have …

The anti-inflammatory effects of PPI in EoE are independent from gastric acid secretion inhibition; despite evidence from observational research, PPIs are the most commonly prescribed first …

2025年2月19日 · The ACG guidelines for EoE emphasize diagnosis based on symptoms of esophageal dysfunction, biopsy findings (≥15 eosinophils per high-power field), and exclusion …

2022年2月26日 · This review article will explore a brief background of EoE, the evolution of PPI therapy for EoE and its proposed mechanisms, efficacy and safety in children and adults, and …

2019年1月19日 · Eosinophilic esophagitis (EoE) is a chronic, immune- or antigen-mediated esophageal disorder characterized clinically by symptoms of esophageal dysfunction and …

The probability of PPI-NR was 72.4-84.5% with 1 risk factor, 87.9-93.8% with 2 risk factors, and 97.2% with all 3 risk factors. Conclusions: Young age, reduced BMI, elevated peripheral …