Polyclonal Antibody for studying ERK1/ERK2. Validated for IP, WB. Available in 2 sizes. Highly specific and rigorously validated in-house, p44/42 MAPK (Erk1/2) Antibody (CST #9102) is ready to ship.

Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) Antibody detects endogenous levels of p44 and p42 MAP Kinase (Erk1 and Erk2) when phosphorylated either individually or dually at Thr202 and Tyr204 of Erk1 (Thr185 and Tyr187 of Erk2).

ERK1 is a protein serine/threonine kinase that is a member of the extracellular signal-regulated kinases (ERKs) which are activated in response to numerous growth factors and cytokines (1). Activation of ERK1 requires both tyrosine and threonine phosphorylation that is mediated by MEK.

Mouse ERK1 / ERK2 Mouse mAb (A10613), validaed in ELISA,WB and tested in Human,Mouse,, Rat. 100% Guaranteed. ABclonal provides trial size antibody samples for target detection. Replacement to Abcam, Santa Cruz, Sigma and CST antibody.

Rockland Anti-ERK1 C-Term Polyclonal, Catalog # 600-401-GP9S. Tested in Western Blot (WB) and ELISA (ELISA) applications. This antibody reacts with Human, Mouse, Rat samples.

本文旨在探讨微波辐射致大鼠海马神经元线粒体损伤中HIF-1 和ERK通路分子表达的改变及意义, 为深入研究微波辐射损伤机制和防治提供新靶标. 2.5, 5 和10 mW/cm2的微波辐射100 只雄性Wistar 大鼠, 辐射时间为6 min/ 次, 5 次/ 周, 连续辐射1 月, 于辐射后6 h, 7 d, 14 d, 1周和2 月, 采用Real-time PCR, Western blot 和免疫组织化学检测海马中hif-1 mRNA, HIF-1 , ERK1/2 和p-ERK1/2 表达. 结果发现, 大鼠海马hif-1 mRNA 和HIF-1 蛋白分别在2.5 和5.

MAP kinase (MAPK, mitogen-activated protein kinase) is also termed as extracellular regulated protein kinase (ERK). It consists of a family of protein kinases. MAP kinase isoforms are widely expressed in the central nervous system, thymus, spleen, heart, lung, kidney, and in high levels in PC12 cells and in fibroblasts.

Phospho-Erk product lists, product citation lists, product selection tools, comparison tables and educational resources for MAPK signaling from Cell Signaling Technology.

2024年10月12日 · ERK1/2是RAF-MEK-ERK信号通路的关键组成部分，在Thr202、Tyr204位点被磷酸化从而激活，进而激活多种与细胞增殖、分化、迁移和血管生成相关的底物（超过160种）。因此ERK1/2的(Thr202, Tyr204)/(Thr185, Tyr187)磷酸化是ERK激活的关键步骤，也是相关研究中不可或缺的检测指标。

2012年8月1日 · ERK1 contains a 17-amino-acid-residue insertion in its N-terminal extension (Fig. 3). The ERK1/2 family contains a 31-amino-acid-residue insertion within the kinase domain (kinase insert domain) that provides additional functional specificity. The cyclin-dependent kinase family also contains a comparable kinase insert domain [14]. In this ...