
What is eDISH ? eDISH= evaluation of Drug-Induced Serious Hepatotoxicity •It is one of the analysis method to assess “Liver Safety Data” for any investigational product. •eDISH is very …
Evaluation of drug-induced serious hepatotoxicity (eDISH ... - PubMed
2011年3月1日 · The eDISH approach is an efficient and effective way to organize and examine large liver safety databases for randomized controlled clinical trials. It greatly facilitates a …
临床研究必备:用SAS绘制eDISH图,轻松应对药物肝毒性挑战
2025年3月4日 · edish 图不仅是一个简单的可视化工具,更是临床研究中不可或缺的分析手段。 通过 eDISH 图,研究者可以快速识别潜在的肝毒性问题,从而优化药物研发流程,减少因肝毒 …
Evaluation of Drug-Induced Serious Hepatotoxicity ( eDISH )
2012年11月21日 · The eDISH tool was conceptualized by Dr John Senior at the FDA to allow medical reviewers to display the peak serum ALT and TB values for every subject in a clinical …
FDA/Composite-eDish-Plot - GitHub
The composite eDISH plot is a visualization of peak on-treatment changes in liver test results both as multiples of the upper limit of normal (xULN) and multiples of the subjects' baseline (xBLN) …
(ALP). eDISH (evaluation of Drug-Induced Serious Hepatotoxicity) is a recently described tool that organizes liver laboratory data by graphically displaying peak serum ALT and TB levels for …
This tool, named eDISH (Evaluation of Drug Induced Serious Hepatotoxicity) now is used by FDA scientists for their regulatory reviews of new drug applications (NDA). The eDISH tool was …
<法规共读>临床试验中的药物性肝损伤识别、处理及评价 - 知乎
eDISH(Evaluation of Drug-induced Serious Hepatoxicity):评价DILI的方法。 3、对可预测严重药物性肝损伤事件的评估. 4、对试验药物导致肝损伤可能性的整体评估. 六、对治疗肝脏疾病 …
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