EIF6 Gene - GeneCards | IF6 Protein | IF6 Antibody
2024年12月24日 · EIF6 (Eukaryotic Translation Initiation Factor 6) is a Protein Coding gene. Diseases associated with EIF6 include Epilepsy, Idiopathic Generalized 4 and Shwachman …
EIF6 - Wikipedia
Eukaryotic translation initiation factor 6 (EIF6), also known as Integrin beta 4 binding protein (ITGB4BP), is a human gene. [5] Hemidesmosomes are structures which link the basal lamina …
eIF6 rebinding dynamically couples ribosome maturation and …
2022年3月23日 · We set out to further validate the hypothesis that eIF6 dynamically rebinds to post-termination cytoplasmic 60S ribosomal subunits by engineering a transgenic eIF6 mouse …
Targeting of eIF6-driven translation induces a metabolic ... - Nature
2021年8月12日 · Reduction of eIF6 levels protects the liver from disease progression. eIF6 depletion blunts lipid accumulation, increases fatty acid oxidation (FAO) and reduces …
EIF6 eukaryotic translation initiation factor 6 [ (human)]
Studies indicate that eukaryotic translation initiation factor 6 (eIF6) is a central regulator of metabolism independent from mTOR protein and myc proto-oncogene protein (Myc). Propose …
eIF6 coordinates insulin sensitivity and lipid metabolism by …
2015年9月18日 · Here we show that reduction of insulin-regulated translation in mice heterozygous for eIF6 results in normal glycaemia, but less blood cholesterol and triglycerides. …
真核翻译起始因子 6（EIF6）基因 | MCE - MCE-生物活性 ...
真核翻译起始因子 6： 半桥粒是连接基底层和中间丝细胞骨架的结构。半桥粒的一个重要功能成分是整合素 beta-4 亚基 (ITGB4) ，这是一种含有两个 III 型纤连蛋白结构域的蛋白质。由该基因 …
eIF6 promotes the malignant progression of human hepatocellular ...
2021年5月20日 · Although emerging studies indicate that eIF6 is aberrantly expressed in various types of cancers, the functions and underlying molecular mechanisms of eIF6 in the …
mTOR 独立途径的翻译控制：eIF6 如何组织代谢 ... - X-MOL
2016年12月2日 · 真核起始因子 6 (eIF6) 是 60S 核糖体成熟所必需的因子。 eIF6 还充当细胞质翻译起始因子，位于生长因子刺激的下游。 eIF6 在几种肿瘤类型中上调。 小鼠模型的数据表 …
Sequestration of ribosomal subunits as inactive 80S by targeting eIF6 …
2024年12月27日 · Introduction. Assembly of ribosomal subunits is a complex process that spans the nucleolus to cytoplasm and requires several conserved trans-acting factors ().Eukaryotic …