The epithelial sodium channel (ENaC), (also known as amiloride-sensitive sodium channel) is a membrane-bound ion channel that is selectively permeable to sodium ions (Na +). It is …

The SCNN1A gene encodes for the α subunit of the epithelial sodium channel ENaC in vertebrates. ENaC is assembled as a heterotrimer composed of three homologous subunits α, …

2024年12月25日 · This gene encodes the alpha subunit, and mutations in this gene have been associated with pseudohypoaldosteronism type 1 (PHA1), a rare salt wasting disease resulting …

2016年4月1日 · The epithelial sodium channel (ENaC) is composed of three homologous subunits and allows the flow of Na(+) ions across high resistance epithelia, maintaining body salt and …

The apical membrane epithelial Na+ channel subunit (ENaC) in series with the basolateral Na+/K+-ATPase mediates collecting duct Na+ reabsorption. Aldosterone induces αENaC …

The SCNN1A gene provides instructions for making one piece, the alpha subunit, of a protein complex called the epithelial sodium channel (ENaC). The channel is composed of alpha, …

Determination of genomic sequences of many eukaryotic species has provided ENaC gene sequences from a broad spectrum of vertebrates. Comparison of ENaC gene and protein …

上皮钠通道 (ENaC) 由三个同源亚基组成，允许 Na(+) 离子流过高电阻上皮细胞，维持体内盐和水的稳态。 肾小管中 ENaC 依赖性 Na(+) 重吸收通过调节渗透压来调节细胞外液 (ECF) 体积和 …

2018年1月1日 · ENaC is generally located at the apical surface of polarized epithelial cells in tight or high-resistance epithelia in the organs including kidney, lung, sweat glands, salivary glands, …

2016年4月1日 · We compared the sequences of ENaC orthologs from 20 species and established criteria for the identification of ENaC orthologs and paralogs, and their distinction from other …