Extracellular Signal-Regulated Kinases Modulate DNA Damage …
Furthermore, ERK activation mediates adriamycin and ETOP-induced up-regulation of glucose transporter 3 in HeLa cells as well as playing a role in IR-induced activation of NF-κB . Taken …
Dual effects of active ERK in cancer: A potential target for
2020年8月20日 · In this context, the present review describes the associations between ERK signaling, cancer and IR, and discusses the association between ERK and its pro-survival …
Adaptive ERK signalling activation in response to therapy and …
2020年5月19日 · Here we addressed extracellular signal-regulated kinase 1/2 (ERK1/2) regulation by cetuximab or fractionated irradiation (IR) and conducted in silico prognostic evaluation of …
4-辛基衣康酸酯通过 ERK 信号激活促进血管生成，从而减轻心肌缺 …
在细胞培养研究中，4-oi 促进内皮细胞增殖和迁移，由丝裂原活化蛋白激酶 （mapk） 信号通路激活介导，特别是通过细胞外信号调节激酶 （erk） 信号传导。
MEK/ERK pathway protects ionizing radiation-induced loss of ...
2002年8月16日 · Here we demonstrate that MEK/ERK-mediated signals selectively inhibit IR-induced loss of mitochondrial membrane potential (ΔΨ m) and subsequent cell death. In …
Biological Rationale for Targeting MEK/ERK Pathways in Anti …
ERK1 and ERK2 (ERKs), two extracellular regulated kinases (ERK1/2), are evolutionary-conserved and ubiquitous serine-threonine kinases involved in regulating cell signalling in …
Ionizing radiation–induced MEK and Erk activation does not …
1998年11月1日 · Purpose: Ionizing radiation (IR) triggers several intracellular signaling cascades that have commonly been regarded as mitogenic, including the Raf–MEK–Erk kinase cascade. …
ERK 通路 | Cell Signaling Technology
MAPK/Erk 信号级联放大通过生长和分化中涉及的各种不同受体进行激活，包括受体酪氨酸激酶 (RTKs)、整合素以及离子通道。 由不同的刺激物激活的级联反应的特定组分差异较大，但通 …
Anti-Vascular Endothelial Growth Factor Antibody Suppresses ERK …
2016年8月11日 · VEGF and extracellular signal-regulated kinase (ERK) were increased in IR-induced ALI. Administration of preconditioning anti-VEGF antibody significantly suppressed …
IR-A/IGF-1R-mediated signals promote epithelial-mesenchymal …
2018年11月14日 · In this study, we presented our novel findings that IR-A/IGF-1R, by activating PI3K/AKT and ERK pathway, induce multiple oncogenic phenotypes in EC cells.