2015年9月1日 · A quite simple and rapid TLC-densitometric method for the identification of α-escin (Aescin) in bulk drug substances was developed. In so doing, different chromatographic conditions, including...

A partial least-squares calibration (PLS) method has been developed for simultaneous quantitative determination of escin (ES) and diethylamine salicylate (DAS) in pharmaceutical preparations. The resolution of these mixtures has been accomplished

2006年4月21日 · A thin-layer chromatographic (TLC) method is developed to analyze the total saponin content, also referred to as the aescin content, in a herbal medicinal product (HMP) containing two dry extracts in capsules. The capsules contain 250 mg of Aesculus hippocastanum dry extract, 120 mg of Vitis vinifer …

1999年11月9日 · A practical and reliable method for the quantitative determination of escin in pharmaceuticals was developed. The TLC–densitometric determination was performed without using spray or dipping reagents in order to provide a more rapid and simple analytical procedure.

A practical and reliable method for the quantitative determination of escin in pharmaceuticals was developed. The TLC-densitometric determination was performed without using spray or dipping reagents in order to provide a more rapid and simple analytical procedure.

2015年11月26日 · A quite simple and rapid TLC-densitometric method for the identification of α-escin (Aescin) in bulk drug substances was developed. In so doing, different chromatographic conditions, including various mobile and stationary phases, were tested.

Table 1 summarizes the results of a set of TLC-densitometric measurements of α-escin (R F and λ max ) which has been gathered through examining all applied chromatographic plates developed...

2017年8月30日 · A rapid and sensitive LC–MS–MS method for the simultaneous determination of escin Ia and isoescin Ia in rat plasma, urine, feces and bile samples was developed and validated.

Escin (Aescin) is a natural mixture of triterpene saponins isolated from the seeds of the horse chestnut (Aesculus hipocastanum). The saponins present in escin belong to two series of isomers, α-escin and β-escin [3]. However, data drawn from current literature demonstrate that isomer a shows lower pharmacological activity than β [10].

1999年11月9日 · Escin in pharmaceutical oral dosage forms: quantitative densitometric HPTLC determination. The described method was successfully employed to identify α-escin in commercial samples that were in an oral dosage form (tablets) and also in the form of gel containing 20 mg of α-Escin. Ö. Dönmez A. Bozdoğan G. Kunt.