2023年10月1日 · EUD is a superior predictor of in vitro cell survival than other metrics sometimes used in the SFRT literature, including mean dose, maximum dose, and valley dose. The reported studies provide some evidence that SFRT may increase the therapeutic ratio by producing spatial dose distributions that effectively reduce normal-tissue damage with ...

Equivalent Uniform Dose (EUD) is a superior predictor of cell survival than absorbed dose. Methods: Absorbed dose parameters were compared to the Equivalent Uniform Dose to assess their predictive value for the relative effectiveness of uniform and SFRT with X-rays. A Bayesian bootstrap technique was utilized to

探究生物等效均匀剂量 (EUD)在非小细胞肺癌放疗调强计划应用中的剂量学意义和临床价值。 筛选本科已经接受调强放疗的ⅢB期非小细胞肺癌患者20例，其中内靶区 (ITV)处方剂量66 Gy，计划靶区 (PTV)处方剂量60 Gy。 分成两组进行剂量优化分析对比，对照组 (n ＝10)用物理优化方法进行剂量约束，观察组 (n ＝10)把危及器官 (食道、心脏、肺、脊髓)的剂量约束条件加入EUD函数优化的剂量约束，其他剂量约束条件不变。 比较这两组是否具有剂量学差异。 观察组PTV和ITV的 …

eud 的概念用于求解一个不均匀剂量分布的等 效平均剂量，这个剂量不同于一般数学上的算 术平均剂量，它具有生物效应上的意义，因此 eud 也可以称为生物等效均匀剂量。

2013年12月13日 · Typically EUD is between the minimum and mean dose for tumors and between the mean and maximum dose for critical structures (especially serial organs). EUD can be a useful endpoint in evaluating treatment plans with non-uniform dose distributions for 3D conformal radiotherapy (3D-CRT) and intensity-modulated radiotherapy (IMRT) .

2022年8月26日 · 立体定向全身放射治疗（SBRT）用于早期非小细胞肺癌的放射治疗时，通常采用不同的分次模式。 最近一次研究（Corso et al.，2017）中回顾了这些分次模式的特征（称为低分次）是相对较少的分次数（即五次或更少）和高分次剂量（10Gy或更大）。 当生物有效剂量（BED）>100 Gy时，局部复发率和3年总生存率分别为8.1%和88.4%。 相反，当BED<100 Gy时，报告的局部复发率和3年生存率分别为26.4%和69.4%。 如上所述，现在存在多种SBRT治疗 …

2020年11月27日 · Converting EUD SBRT into standard 2‑Gy fractions by the LQ formalism produced significantly larger EUD CFRT than the USC formalism, particularly for low \ (\alpha /\beta\) ratios and large fraction dose.

Equivalent uniform dose (EUD) is the absorbed dose that, when homogeneously given to a tumor, yields the same mean surviving clonogen number as the given non-homogeneous irradiation. EUD is used as an evaluation tool under the assumption that two ...

2022年1月11日 · Predictive ability of EUD V D (EUD of V D) for radiation-induced brain injury was assessed by receiver operating characteristics curve (ROC) and area under the curve (AUC). The optimal volume-effect parameter a of EUD was selected when AUC was maximal (mAUC).

2023年10月1日 · EUD is a superior predictor of in vitro cell survival than other metrics sometimes used in the SFRT literature, including mean dose, maximum dose, and valley dose. The reported studies provide some evidence that SFRT may increase the therapeutic ratio by producing spatial dose distributions that effectively reduce normal-tissue damage with ...