2024年12月25日 · FABP5 (Fatty Acid Binding Protein 5) is a Protein Coding gene. Diseases associated with FABP5 include Psoriasis and Autism Spectrum Disorder . Among its related pathways are Innate Immune System and Developmental Cell Lineages .

2024年4月23日 · Here, we identified ferroptosis marker antigens by analyzing surface protein dynamics and discovered a single protein, Fatty Acid-Binding Protein 5 (FABP5), which was stabilized at the...

4 天之前 · FABP5 levels in serum (patient), tumor (PDX and HCC1806 xenografts) and TIF (from HCC1806 xenografts) were ascertained using the Human FABP-5 ELISA kit (Invitrogen, EH178RB) according to the manufacturer’s instructions. Briefly, 100 μl sample and standards were added to appropriate wells precoated with an FABP5 capture antibody.

FABP5 promotes tumor angiogenesis via activation of the IL6/STAT3/VEGFA signaling pathway in hepatocellular carcinoma. FABP5 promotes lipolysis of lipid droplets, de novo fatty acid synthesis and activation of NF-kappaB signaling in cancer cells.

2022年4月4日 · In recent years, fatty acid binding protein 5 (FABP5), also known as fatty acid transporter, has been widely researched with the help of modern genetic technology. Emerging evidence suggests its critical role in regulating lipid transport, homeostasis, and metabolism.

2023年7月1日 · Fatty acid binding protein 5 (FABP5, or epidermal FABP) is an intracellular chaperone of fatty acid molecules that regulates lipid metabolism and cell growth. In patient-derived tumours, FABP5 expression is increased up to tenfold, often co-expressed with other cancer-related proteins.

Fatty acid-binding protein 5 (FABP5) is an important member of the FABP family and plays a vital role in the metabolism of fatty acids. However, few studies have examined the role of FABP5 in pathological cardiac remodeling and heart failure.

2020年10月30日 · FABP5 enhances HIF-1α activity by promoting HIF-1α synthesis while disrupting FIH/HIF-1α interaction at the same time. Oleic-acid treatment activates the FABP5/HIF-1α axis, thereby promoting...

2015年8月11日 · The authors focus on FABP4 and FABP5, the most abundant FABPs in adipose tissue, and discuss how targeting these proteins might be exploited to treat metabolic diseases.

2025年2月27日 · Silencing of FABP5 leads to significant alterations in cell dynamics, metabolism, and NF-κB activity, highlighting its potential as a therapeutic target. Our findings unveil a reciprocal relationship between lipid metabolism and inflammation in PM, providing a foundation for targeted therapeutic strategies.