For instance, an ideal FDC would be the ARB, azilsartan and the CCB, amlodipine in a pill form that is scored for ease of splitting and in a convenient dosage. However, at least in the United …

When a combination drug product (whether fixed-dose or not) is a "pill" (i.e., a tablet or capsule), then it may also be a kind of "polypill" or combopill. Initially, fixed-dose combination drug …

2023年5月9日 · Fixed‐dose combination (FDC) antihypertensive products improve blood pressure control and adherence among patients with hypertension. It is unknown to what degree …

2020年10月14日 · Fixed-dose combination (FDC), also known as “single-pill combination,” antihypertensives deliver two or more antihypertensive classes within one pill and offer a more …

The aim of the following practical review is to help physicians choosing the right single-pill FDC, or the right combination of two FDC pills, for the right patient in the daily clinical practice, based …

2023年12月21日 · In this study we report the in-trial cost effectiveness of a single FDC pill strategy plus aspirin using individual participants data (IPD) from a meta-analysis of the three …

2019年5月31日 · Trials of FDC pills comprising three half-dose or four quarter-dose BP-lowering drugs have shown substantial efficacy. In this Review, we summarize the current evidence on …

2018年6月11日 · Our study suggests that FDC formulations are associated with better medication adherence and clinical outcomes. Using FDC rather than multipill therapy represents a simple …

2011年11月1日 · In spite of advances in prevention and treatment, the burden of cardiovascular diseases is increasing. A fixed-dose combination (FDC) pill, or “polypill,” composed of …

Fixed-dose combination (FDC) therapies are hypothesized to enhance compliance by decreasing the number of required pills. Objective: The objective of the study is to compare adherence of …