INT-2 proto-oncogene protein also known as FGF-3 is a protein that in humans is encoded by the FGF3 gene. [5] FGF-3 is a member of the fibroblast growth factor family. FGF3 binds to …

酸性fgf（afgf）和碱性fgf（bfgf）是fgf的原型成员，因其等电点不同而得名。它们在氨基酸序列上有55%的同源性，大小相似。基于系统发育分析，fgfs可分为七个亚家族。也有研究提出存在8 …

2024年12月25日 · FGF3 (Fibroblast Growth Factor 3) is a Protein Coding gene. Diseases associated with FGF3 include Deafness, Congenital, With Inner Ear Agenesis, Microtia, And …

This gene was identified by its similarity with mouse fgf3/int-2, a proto-oncogene activated in virally induced mammary tumors in the mouse. Frequent amplification of this gene has been …

该基因是通过其与小鼠 fgf3/int-2 的相似性来鉴定的，fgf3/int-2 是一种在小鼠病毒诱导的乳腺肿瘤中激活的原癌基因。 已在人类肿瘤中发现该基因的频繁扩增，这可能对肿瘤转化和肿瘤进展 …

2025年1月4日 · Homozygous FGF3 mutations result in congenital deafness with inner ear agenesis, microtia, and microdontia. Syndromic congenital sensorineural deafness, microtia …

2020年9月2日 · Fibroblast growth factors (FGFs) are broad-spectrum mitogens and regulate a wide range of cellular functions, including migration, proliferation, differentiation, and survival....

The FGF3 gene provides instructions for making a protein called fibroblast growth factor 3 (FGF3). This protein is part of a family of proteins called fibroblast growth factors that are …

2025年2月8日 · Homozygous mutations in fibroblast growth factor 3 are associated with a new form of syndromic deafness characterized by inner ear agenesis, microtia, and microdontia. …

Fgf3 and Fgf10 (602115) signals localized to the leading zone are required for rosette formation, atoh1a expression, and primordium migration. Nechiporuk and Raible (2008) proposed that …