2016年4月21日 · By stacking on the G-tetrad, the ThT probe exhibited highly specific recognition of RNA G-quadruplex structures with striking fluorescence enhancement compared with other RNA forms. The...

2021年1月4日 · 近年来，研究发现tht能够特异性结合g-四链体（g4），使其荧光得以增强。 基于此荧光现象，G4/ThT被广泛地用作荧光指示剂构建非标记型生物传感，实现了对多种分析物的检测。

2018年2月8日 · Herein, fluorescent dye ThT-E, a derivative of the known fluorescence probe Thioflavin T (ThT), was designed and synthesized to effectively differentiate various G-quadruplex structures from...

We report a new Föster resonance energy transfer (FRET) system that uses a special dye, thioflavin T (ThT), as an energy acceptor and a water-soluble conjugated polymer (CP) with high fluorescence as an energy donor.

硫黄素 T (ThT) 是一种苯并噻唑染料，在与淀粉样蛋白原纤维结合后表现出增强的荧光，通常用于离体和体外诊断淀粉样蛋白原纤维。 在水溶液中，发现硫黄素 T 以胶束形式存在，其浓度通常用于通过荧光测定法监测原纤维 (~10 -20 μM)。

2020年9月5日 · ThT, a commercially available water-soluble benzothiazole fluorochrome, shows weak fluorescence emission in a free state. However, ThT could recognize the structures of G-quadruplex through intercalation, groove-binding and end stacking, thus significantly enhancing its fluorescence intensity [23].

硫磺素 T (ThT) 在 G-四链体结构（例如由人类端粒基序形成的结构）存在的情况下会发出荧光。 在本报告中，我们扩展并概括了这些观察结果，并表明这种染料可用作方便且特异的四链探针。 在大多数（但不是全部）G4 形成序列存在的情况下，我们观察到 ThT 荧光发射大幅增加，而对照双链体和单链的存在对发射的影响更为有限。 这种差异行为使我们能够设计一种高通量检测来检测 G4 的形成。 可以使用简单的荧光读板仪并行测试数百种不同的寡核苷酸的 G4 形成。

Thioflavin T (ThT) becomes fluorescent in the presence of the G-quadruplex structure such as that formed by the human telomeric motif. In this report, we extend and generalize these observations and show that this dye may be used as a convenient and specific quadruplex probe.

2018年12月1日 · Thioflavin T (ThT), a water-soluble fluorescence probe and the conventional dye for the detection of amyloid fibrils has recently been demonstrated to recognize and bind nucleic acids. It induces the formation of G-quadruplex (G4) structure and appears as a sensor by emitting enhanced fluorescence.

硫黄素 t (tht) 和 n-甲基中卟啉 ix (nmm) 在大多数 g4 存在下都会发荧光，但据报道，当使用 tht 时，凝血酶结合适体 (tba) 是已知 g4 形成寡核苷酸的唯一例外作为鉴定 g4 形成的高通量测定。