SOX9 regulated matrix proteins are increased in patients serum …
2018年12月17日 · A reduction in mRNA and protein levels of 5 SOX9 targets, namely Opn, Gpnmb, Fn1, Sparc, and Vim was uncovered (Fig. 2B–D). Compared to quiescent HSC …
Macrophages regulate vascular smooth muscle cell function …
2022年12月1日 · The upregulation of FN1, SOX9 was observed during atherosclerosis. And the higher expression of SOX9 and lower expression of FN1 were shown in AAV-sgIL-1β group, …
Endothelial cells drive organ fibrosis in mice by inducing …
2024年2月28日 · Overexpression of Sox9 induced the expression of Ccn2 or Fn1 in ECs that coexpressed one or both endothelial markers (fig. S27G). These results indicated that …
Insights into the implementation of Fibronectin 1 in the cartilage ...
2022年4月1日 · The proposed molecular mechanism of fibronectin 1 (FN1) in the chondrocyte. FN1 mediates chondrocyte signaling through activating α5β1 and αvβ3 integrins, which …
ATDC5细胞系增殖分化各阶段标志物表达差异的比较 - 百度学术
通过基因与蛋白水平的检测发现,Fn1和Sox9的mRNA表达量在7 d时达到峰值,在细胞进入成熟阶段后显著降低,Sox9及Fn1的蛋白表达趋势与其mRNA表达趋势一致；Col2的mRNA及蛋白表达 …
SOX9 regulated matrix proteins are increased in patients …
2018年12月17日 · In this study, transcriptomic approaches of Sox9-abrogated myofibroblasts identified >30% of genes regulated by SOX9 relate to the ECM. Further scrutiny of these data …
397620 - Gene ResultFN1 fibronectin 1 [ (pig)] - National Center …
The expression of the differentiation and stemness genes, FN1 and SOX9, is accompanied by cell proliferation. The obtained results suggest that propolis modifies fibronectin metabolism in the …
Tomo-Seq Identifies SOX9 as a Key Regulator of Cardiac Fibrosis …
2017年7月19日 · We show that SOX9 is induced in response to ischemic injury and that in vivo loss of SOX9 after myocardial infarction blunts the cardiac fibrotic response on damage, …
transcription factors SOX9 and SOX5/SOX6 cooperate genome …
2015年7月6日 · Using the RCS cell line as a faithful model for proliferating/early prehypertrophic growth plate chondrocytes, we uncover that SOX6 and SOX9 bind thousands of genomic …
SOX9 regulated matrix proteins are increased in patients …
2018年12月17日 · A reduction in mRNA and protein levels of 5 SOX9 targets, namely Opn, Gpnmb, Fn1, Sparc, and Vim was uncovered (Fig. 2B–D). Compared to quiescent HSC …