Fatty acid-binding proteins (FABPs) are members of the intracellular lipid-binding protein (iLBP) family and are involved in reversibly binding intracellular hydrophobic ligands and trafficking them throughout cellular compartments, including the peroxisomes, mitochondria, endoplasmic reticulum and nucleus. [2] .

脂肪酸结合蛋白(fatty acid-binding protein,FABP)是胞内脂质结合蛋白超家族成员,存在于脊椎动物和无脊椎动物的细胞内,在长链脂肪酸的摄取、转运及代谢调节中发挥重要作用,并涉及生物体的其他生命过程。

Also known as fatty acid-binding proteins (FABPs), these are a group of proteins that coordinate lipid trafficking and signalling in cells, and some isoforms...

脂肪酸结合蛋白(FABPs) 是编码15 kDa蛋白质的多基因家族的成员,它具有结合疏水生物分子如脂肪酸的能力( 表1)。 到目前为止,在哺乳动物中至少已经发现9种FABPs,根据它们在特定组织的高表达可以分别命名为:肝脏型(liver-FABP) 、肠型(intestinal-FABP)、心脏型(heart-FABP) 、脂肪型(adipose-FABP)、表皮型(epidermal-FABP) 、回肠型(ileum-FABP)、脑型(brain-FABP) 、髓鞘型(myelin-FABP)和睾丸型分别和以上分型相对应。 (testis-FABP)。 FABP1~9 FABP10 …

2015年8月11日 · Fatty acid-binding protein, adipocyte (FABP4) regulates metabolic and inflammatory pathways, and in mouse models its inhibition can improve type 2 diabetes mellitus and atherosclerosis

Fatty acid-binding protein 4 (FABP4), also known as adipocyte FABP (A-FABP) or aP2, is mainly expressed in adipocytes and macrophages and plays an important role in the development of insulin resistance and atherosclerosis in relation to metaflammation.

Fatty acid binding protein (FABP) is one of the intracellular proteins, with a low molecular weight of approximately 15 kDa, that plays important roles in the transportation and metabolism of long-chain fatty acids. FABP family proteins could be used as …

Fatty acid binding protein (FABP), low molecular weight proteins of 14–15 kDa, transport long-chain fatty acids through cell membranes and mediate intracellular transport as a chaperone. Nine FABP isoforms have been identified (Veerkamp and Zimmerman, 2001), of which FABP3, 5, and 7 are expressed in the brain (Owada, 2008; Kurtz et al., 1994 ...

Purpose of review: Fatty acid-binding proteins (FABPs) are a family of small, abundant proteins with highly tissue-specific expression patterns whose different functions remain incompletely understood.

2020年8月20日 · Fatty acid binding proteins (FABPs) serve as intracellular chaperones for fatty acids and other hydrophobic ligands inside cells. Recent studies have demonstrated new functions of individual members of the FABP family. This Snapshot describes the overall functions of FABPs in health and disease and …