Fatty acid binding protein 4 regulates doxorubicin-induced renal …
2025年2月25日 · Fatty acid-binding protein 4 (FABP4), a key adipokine mainly expressed in adipocytes, is strongly associated with kidney dysfunction and kidney disease. This study aims …
Antitumor efficacy and potential mechanism of FAP-targeted
2024年6月3日 · Herein, we demonstrate that 68 Ga/ 177 Lu-labeled LNC1004 exhibits increased uptake and prolonged retention in MC38/NIH3T3-FAP and CT26/NIH3T3-FAP tumor …
Fatty acid mobilization from adipose tissue is mediated by CD36 ...
2021年7月27日 · We demonstrated that lipolysis induction in adipocytes triggered CD36 deacylation and deglycosylation, as well as its dissociation from interacting proteins, prohibitin …
脂肪酸结合蛋白(FABPs) 是编码15 kDa蛋白质的多基因家族的成员,它具有结合疏水生物分子如脂肪酸的能力( 表1)。 到目前为止,在哺乳动物中至少已经发现9种FABPs,根据它们在特定组织的 …
FABP4-mediated lipid metabolism promotes TNBC ... - ScienceDirect
2024年11月1日 · FABP4 regulates BCSC activity and TNBC progression through CPT1b-mediated fatty acid oxidation and ROS production. Loss of FABP4 attenuates obesity …
脂肪酸结合蛋白4在肥胖相关肿瘤中的作用综述
脂肪酸结合蛋白4（fatty acid binding protein-4，FABP4）是一种主要在脂肪细胞和巨噬细胞表达的小分子蛋白，负责参与脂肪酸转运和应答反应。 研究发现，FABP4水平不仅与体脂含量相 …
Development of a humanized anti-FABP4 monoclonal antibody for …
2024年7月25日 · In exploring obesity/breast cancer risk, we have identified adipose fatty-acid binding protein (A-FABP, also known as FABP4, aP2) as a new molecular mechanism linking …
脂肪酸结合蛋白4 - 百度百科
FABP4 基因缺陷小鼠的研究表明， 这种脂质载体与新陈代谢综合征、 炎症和动脉粥样硬化等疾病的发生存在密切的关系， 它能够调节炎症的发生发展和新陈代谢、 抵抗动脉粥样硬化的发 …
A New Insight into Fatty Acid Binding Protein 4 Mechanisms and ...
FABP4, primarily expressed in adipocytes, monocytes, and macrophages, is integrated into signaling networks that influence immune responses and insulin activity. It has been linked to …
脂肪细胞通过诱导FABP4表达促进卵巢癌细胞迁移和介导对卡铂耐 …
结果发现，脂质代谢蛋白质，如FABP4、CD36和乙醇脱氢酶（ADH）1蛋白的表达随着共培养时间的增加而升高。 临床样本免疫组化结果显示，ADH1B，CD36和FABP4在上皮肿瘤组织的表 …