脂肪酸的转运与氧化分解 - 知乎 - 知乎专栏
FATP是脂肪酸转运蛋白（fatty acid transport proteins），主要用于运输长链脂肪酸，至少有六种（FATP1-6），各有不同的专一性和组织分布。 脂肪酸与转运蛋白结合后，表观pKa从水溶液 …
FABP5 controls macrophage alternative activation and ... - Cell Press
2022年11月15日 · In mice with myeloid-specific deletion of fatty acid-binding protein 5 (FABP5), OVA-induced allergic airway inflammation (AAI) is significantly exacerbated by increasing …
脂肪酸摄取和脂肪酸氧化-脂肪酸（fatty acid）代谢 - 每日生物评论
2023年11月23日 · 脂肪酸氧化（Fatty Acid Oxidation，FAO）是肉碱棕榈酰转移酶 1和2（CPT1和CPT2）将长链脂肪酸转运到线粒体基质后经羟酰基辅酶a氧化为乙酰辅酶a、NADH和FADH2 …
Regulation of macrophage functions by FABP-mediated …
Fatty acid binding proteins (FABPs) represent a family of evolutionarily conserved proteins facilitating lipid transport, metabolism and responses inside cells. More specifically, adipose …
Metabolic functions of FABPs—mechanisms and therapeutic ... - Nature
2015年8月11日 · In this Review we discuss the roles and regulation of both intracellular and extracellular FABP actions, highlighting new insights that might direct drug discovery efforts …
Fatty acid-binding proteins: role in metabolic diseases and
Also known as fatty acid-binding proteins (FABPs), these are a group of proteins that coordinate lipid trafficking and signalling in cells, and some isoforms are...
Fatty acid binding protein 5 suppression attenuates obesity …
2024年4月25日 · Here we identify fatty acid binding protein 5 (FABP5) as a driver of obesity-induced HCC. Analysis of transformed cells reveals that FABP5 inhibition and silencing …
《细胞报告》：中科院动物所赵勇团队揭示FABP5调控巨噬细胞替 …
2022年11月16日 · 该研究发现，脂肪酸结合蛋白FABP5主要通过调节长链不饱和脂肪酸 (LCUFAs) -PPARγ-ATP-STAT6通路调节巨噬细胞M2极化，进而调节过敏性哮喘。 该研究为过敏性哮喘 …
A Critical Role of Fatty Acid Binding Protein 4 and 5 (FABP4/5
2013年11月14日 · Cytoplasmic fatty-acid-binding proteins (FABPs) actively facilitate the transport of lipids to specific compartments in cells. FABP4 (also known as aP2/ALBP/A-FABP) and …
Progress in Lipid Research：脂肪酸及其相关蛋白质在神经、心血 …
2021年7月，东芬兰大学、印度医学研究委员会、奥斯陆大学的相关研究人员在《Progress in Lipid Research》（IF: 16.2）上发表了题为“Fatty acids and evolving roles of their proteins in …