Fanconi anaemia, complementation group A, also known as FAA, FACA and FANCA, is a protein which in humans is encoded by the FANCA gene. [5] It belongs to the Fanconi anaemia …

2024年12月25日 · FANCA (FA Complementation Group A) is a Protein Coding gene. Diseases associated with FANCA include Fanconi Anemia, Complementation Group A and Pituitary …

六个蛋白(fanca, fancc, fance, fancf, fancg,fancl)组合成一个多亚基核复合物激活fancd2的单泛素化(fancd2-ub), fancd2单泛素化是dna交联修复途径最重要的步骤，因为单泛素化的fancd2作用于 …

范科尼贫血（fa）是常染色体或x连锁隐性遗传性骨髓衰竭性疾病，fa相关基因突变或缺失，导致dna损伤后修复调节以及dna链间交联修复等多个过程异常而致病，最常见的突变基因包 …

The FANCA gene provides instructions for making a protein that is involved in a process known as the Fanconi anemia (FA) pathway. The FA pathway turns on (activates) when the process …

2021年3月15日 · FANCA, FANCC, and FANCG are associated with cytochrome P450-related activities and/or respond to oxidative damage. FANCD2 interacts with FOXO3 in response to …

Fanconi anemia, complementation group A (FANCA) is a gene that encodes a protein that is a member of the Fanconi anemia complementation group. The protein complex functions in the …

In a cell line derived from a proband with Fanconi anemia of complementation group A (FANCA; 227650), Singh et al. (2009) identified compound heterozygous mutations in the FANCA gene: …

fanca基因编码的蛋白质是范科尼贫血互补组（fanc）的关键成员，其结构可能涉及多个亚型的转录变体。 虽然FANCA直接参与的特定信号通路尚不完全明确，但它在DNA损伤修复和维持基因 …

Mutant FANCA proteins complement the sensitivity of DNA crosslinker mitomycin C at different grades: five proteins (group I) behave like wild-type FANCA, whereas the other proteins are …