2024年12月25日 · FAT4 (FAT Atypical Cadherin 4) is a Protein Coding gene. Diseases associated with FAT4 include Van Maldergem Syndrome 2 and Hennekam Lymphangiectasia …

Protocadherin Fat 4, also known as cadherin family member 14 (CDHF14) or FAT tumor suppressor homolog 4 (FAT4), is a protein that in humans is encoded by the FAT4 gene. [5] …

2023年9月1日 · Here, we report the mechanism by which FAT4 overexpression regulates anti-tumor immunity in cervical cancer by inhibiting PD-L1 N-glycosylation and cell membrane …

对小鼠的研究表明，PCP 信号传导的缺失可能会导致囊性肾病，并且该基因的突变与 Van Maldergem 综合征 2 相关。 已注意到该基因的选择性剪接转录物变体。 [RefSeq 提供，2014 …

The FAT4 gene provides instructions for making a protein that is found in most tissues. Learn about this gene and related health conditions.

大肠癌组织中fat4 的表达和yap 的表达呈负相关（r =-0.434，p＜0.01）。 FAT4 表达阳性者3 年生存率为84.62%，明显高于FAT4 表达阴性者的48.15%，差异有统计学意义（P＜0.01）；YAP …

2023年2月16日 · Here, we determine the co-crystal structure of the human homologs Fat4 and Dachsous1 (Dchs1) to establish the molecular basis for Fat-Dachsous interactions. The …

2019年3月4日 · FAT4 can regulate the activity of PI3K to promote autophagy and inhibit the EMT in part through the PI3K/AKT/mTOR and PI3K/AKT/GSK-3β signaling pathways.

Our study summarized and analyzed the antitumor effect of FAT4 in different tumors comprehensively, which aided in understanding the role of FAT4 in tumorigenesis from the …

Katoh and Katoh (2006) determined that full-length FAT4 encodes a deduced 4,924-amino acid protein with 34 extracellular cadherin repeats. In silico analysis identified FAT4 mRNAs in fetal …