Escherichia coli Nissle 1917 ghosts alleviate inflammatory bowel ...
2023年9月15日 · Escherichia coli Nissle 1917 (EcN) is often used in bacterial drug delivery systems to treat cancer, IBD and other diseases due to its facultative anaerobic property. This …
Layer-by-layer coated probiotics with chitosan and liposomes …
2024年6月1日 · In the current study, we employed FITC-chitosan and Nile Red-labeled liposomes to create fluorescent PCLip@EcN for subsequent identification through confocal laser …
Camouflaging bacteria by wrapping with cell membranes
2019年8月6日 · As a proof-of-concept study, we chose a well-known probiotic bacterium, Escherichia coli Nissle 1917 (EcN), a host bacterium which has been used for treating …
Biomaterials coating for on-demand bacteria delivery: Selective release ...
2021年12月1日 · Here, we report a double-layer coating strategy employing tannic acid (TA) and enteric L100 for probiotics encapsulation to address the delivery challenges after oral …
Identification of an analgesic lipopeptide produced by the …
2017年11月3日 · We characterize lipoamino acids and lipopeptides produced by EcN but not by the mutant by online liquid chromatography mass spectrometry. One of these lipopeptides, …
Improvement of a synthetic live bacterial therapeutic for ...
2021年10月28日 · As a treatment for PKU, Escherichia coli Nissle (EcN) strain SYNB1618 was developed under Synlogic’s Synthetic Biotic™ platform to degrade Phe from within the …
大肠杆菌 Nissle 1917 对肠屏障的保护作用是通过 TLR-4 抑制 …
本研究调查了 大肠杆菌 Nissle 1917 (EcN) 对肠道屏障的保护作用以及在急性严重炎症背景下的机制。 在这项研究中，小鼠接受脂多糖 (LPS) 腹腔注射，有或没有 EcN 给药，以构建内毒素血 …
基于益生元的改良“盾牌”武装益生菌，增强胃肠道应激抵抗力并延 …
Fe-TA@mGN“盾牌”不仅作为动态屏障增强EcN的胃肠道应激抵抗能力，还有助于EcN在肠道定植，并与EcN协同减轻右旋糖酐硫酸钠（DSS）诱导的胃肠道应激反应。
炎症性肠病有“杀手”了，口服益生菌就能治疗 - 上海英拜生物科技 …
2022年8月10日 · 已有研究表明，壳聚糖/海藻酸钠包裹ECN- pe [ECN-pE (C/A)2]可以调节肠道菌群，提高肠道菌群丰富度 (OTU)和多样性 (Shannon多样性指数)缓解肠道炎症。 对ECN进行 …
Escherichia coli Nissle 1917 (EcN) is a beneficial probiotic, whose molecular mechanisms in the prevention of colon cancer are yet to be fully understood. The present study assessed the anti …
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