The CsrA-FliW network controls polar localization of the dual …
2016年5月27日 · Here we investigate CsrA activity control in the absence of antagonizing small RNAs by examining the CsrA regulon in the human pathogen Campylobacter jejuni. We use …
FliW antagonizes CsrA RNA binding by a noncompetitive allosteric ... - PNAS
2016年8月11日 · CsrA is a conserved global regulatory protein that binds to the 5′UTR of target transcripts to control RNA stability or occlude the Shine–Dalgarno sequence and inhibit …
Flagellar Assembly Factor FliW2 De‐Represses
2025年3月25日 · Phylogenetic tree analysis and characteristics of the CsrA and FliW homologs in Proteobacteria. The protein sequences of H. pylori J99 CsrA and its homologs (Table S3) …
FliW and CsrA Govern Flagellin (FliC) Synthesis and Play …
In Bacillus subtilis, flagellin homeostasis and motility are coregulated by flagellar assembly factor (FliW), flagellin Hag (FliC homolog), and Carbon storage regulator A (CsrA), which is referred …
CsrA-FliW interaction governs flagellin homeostasis and a …
Here we discover FliW, the first protein antagonist of CsrA activity that constitutes a partner switching mechanism to control flagellin synthesis in the Gram-positive organism Bacillus …
Robust Stoichiometry of FliW-CsrA Governs Flagellin Homeostasis …
2019年5月21日 · We found that stoichiometry is ensured by genetic architecture, translational coupling, and the ability of CsrA dimer to restrict hag transcript accumulation. We further show …
Microbiology Journal - Wiley Online Library
2011年9月6日 · Here we discover FliW, the first protein antagonist of CsrA activity that constitutes a partner switching mechanism to control flagellin synthesis in the Gram-positive organism …
Control of Clostridioides difficile virulence and physiology by the ...
2025年1月30日 · Analysis of mutations in fliC, fliW, and csrA (and all combinations) on C. difficile pathogenesis indicated that FliW plays a central role in C. difficile virulence as animals …
FliW antagonizes CsrA RNA binding by a noncompetitive …
2016年8月30日 · In γ-proteobacteria, CsrA activity is competitively antagonized by one or more small RNAs (sRNAs) containing multiple CsrA binding sites, but CsrA in bacteria outside the γ …
The CsrA-FliW network controls polar localization of the dual …
2016年5月27日 · Together with the main C. jejuni CsrA antagonist, the FliW protein, flaA mRNA controls CsrA-mediated post-transcriptional regulation of other flagellar genes. RNA-FISH …