2024年12月25日 · FLT1 (Fms Related Receptor Tyrosine Kinase 1) is a Protein Coding gene. Diseases associated with FLT1 include Pre-Eclampsia and Eclampsia. Among its related pathways are Apoptotic Pathways in Synovial Fibroblasts and GPCR Pathway. Gene Ontology (GO) annotations related to this gene include identical protein binding and protein kinase activity.

Soluble fms-like tyrosine kinase-1 (sFlt-1 or sVEGFR-1) is a tyrosine kinase protein with antiangiogenic properties.

2001年2月1日 · Flt-1, also known as vascular endothelial growth factor receptor 1 (VEGFR-1), is a high-affinity tyrosine kinase receptor for VEGF and is expressed almost exclusively on vascular endothelial cells. As an exception, Flt-1 transcript was recently found to be expressed in human peripheral blood monocyt …

Vascular endothelial growth factor receptor 1 is a protein that in humans is encoded by the FLT1 gene. [5] FLT1 is a member of VEGF receptor gene family. It encodes a receptor tyrosine kinase which is activated by VEGF-A, VEGF-B, and placental growth factor.

血管内皮生长因子受体1(vegf r1)也称为flt-1，是血管生成因子vegf (vegf-a)、胎盘生长因子(pigf)和vegf-b的特异性酪氨酸激酶 (rtk) 受体。 根据剪切形式，存在膜型 (mbVEGFR)和可溶性(sVEGFR) 两种形式。

fms 相关受体酪氨酸激酶 1： 该基因编码血管内皮生长因子受体 (VEGFR) 家族的成员。 VEGFR 家族成员是受体酪氨酸激酶 (RTK) ，它包含一个细胞外配体结合区，具有七个免疫球蛋白 (Ig) 样结构域、一个跨膜区段和一个胞质结构域内的酪氨酸激酶 (TK) 结构域。

2001年2月1日 · Flt-1, also known as vascular endothelial growth factor receptor 1 (VEGFR-1), is a high-affinity tyrosine kinase receptor for VEGF and is expressed almost exclusively on vascular endothelial cells. As an exception, Flt-1 transcript was recently found to be expressed in human peripheral blood monocytes.

Flt-1 expression influences apoptotic susceptibility of vascular smooth muscle cells through the NF-kappaB/IAP-1 pathway. Biologically active VEGFR-1 secreted by monocyte-derived mature dendritic cells (mDCs) contributes to their antiangiogenic property by effectively inhibiting angiogenesis in vitro and in vivo.

Vascular endothelial growth factor receptor-1 (VEGFR-1) is a member of the VEGFR family, and binds VEGF-A, PlGF, and VEGF-B. An important feature of VEGFR-1 is that, unlike other VEGFR genes, it expresses two types of mRNA, one for a full-length receptor and another for a soluble short protein known …

血管内皮生长因子受体1(vegf r1)也称为flt-1，是血管生成因子vegf (vegf-a)、胎盘生长因子(pigf)和vegf-b的特异性酪氨酸激酶 (rtk) 受体。 根据剪切形式，存在膜型 (mbVEGFR)和可溶性(sVEGFR) 两种形式。