Flupirtine is an aminopyridine that functions as a centrally acting non- opioid analgesic that was originally used as an analgesic for acute and chronic pain [5] but in 2013 due to issues with liver toxicity, the European Medicines Agency restricted its use to acute pain, for no more than two weeks, and only for people who cannot use other paink...

氟吡汀，氟吡汀是作为中枢作用的非阿片样镇痛药的氨基吡啶。 它于1984年首次在欧洲上市，主要以Katadolon，Trancolong，Awegal，Efiret，Trancopal Dolo和Metanor等名称销售。 像奈福泮一样，它在镇痛药中是独一无二的，因为它是非阿片样物质，非NSAID，非甾体中枢作用镇痛剂。 临床镇痛效果较美沙酮稍弱，用手术后、外伤、烧伤所致疼痛。 主要用于术后痛、头痛、创伤及烧伤所致的疼痛。 1口服：每次100mg，每天3～4次，严重者每次200mg，每天3次，最大剂量 …

Flupirtine is neither an opioid nor a non steroidal anti-inflammatory drug (NSAID) producing its analgesic action through blockade of glutamate N-methyl-D-aspartate receptor. It is devoid of adverse effects of routinely used analgesic drugs, but …

Flupirtine is a centrally acting, non-opioid analgesic that is available in a number of European countries for the treatment of a variety of pain states. The therapeutic benefits seen with flupirtine relate to its unique pharmacological properties. Flupirtine …

Flupirtine is a novel non-opiate centrally acting analgesic agent with muscle relaxant properties, advocated for use in a number of pain states. Preliminary evidence suggests that flupirtine 100 to 200mg orally or 150mg rectally 3 to 4 times daily (maximum daily …

2008年3月19日 · Flupirtine is a pyridine derivative that is in clinical use as a nonopioid analgesic. It was approved for the treatment of pain in 1984 in Europe. It is not approved...

Background: Flupirtine is a nonopioid drug without antipyretic or antiphlogistic properties and with a favorable tolerability. It constitutes a unique class within the group of nonsteroidal analgesics and displays a peculiar pharmacodynamic profile that invites the investigation of applications beyond the pain-relieving effect.

马来酸氟吡汀是一种新型的 止痛药，其作用机制是一种选择性神经原钾通道开放剂 (Selective Neuronal Potassium Channel Opener, SNEPCO)，具有止痛，肌肉松弛和神经保护三重功效。 主要用于各种类型的中等程度的急性疼痛的治疗，如外科手术、创伤等引起的疼痛以及头痛/ 偏头痛及腹部痉挛等。 【药品名称】 通用名称：马来酸氟吡汀胶囊. 英文名称：Flupirtine Maleate Capsules. 汉语拼音：Malaisuan Fubiting Jiaonang.

Flupirtine is a pyridine derivative that is in clinical use as a nonopioid analgesic. It was approved for the treatment of pain in 1984 in Europe. It is not approved for use in the U.S. or Canada, but is currently in phase II trials for the treatment of fibromyalgia.

2024年12月9日 · Flupirtine is used in treatment of pain relief. Flupirtine decreases the perception of pain by blocking the transmission of pain signals to the brain.