2018年7月9日 · Fetal and neonatal alloimmune thrombocytopenia (FNAIT) is an uncommon disorder (<1 out of 1000 births) in which maternal-fetal platelet incompatibility leads to formation of maternal antibodies that result in fetal and neonatal thrombocytopenia.

Fetal/neonatal alloimmune thrombocytopenia (FNAIT) is a relatively rare condition (1/1000–1/2000) that was granted orphan status by the European Medicines Agency in 2011. Clinical consequences of FNAIT, however, may be severe. A thrombocytopenic fetus or new-born is at risk of intracranial hemorrhage that may result in lifelong disability or death.

胎儿及新生儿同种免疫性血小板减少症（fetal and neonatal alloimmune thrombocytopenia, FNAIT）是因孕妇同种免疫性血小板抗体进入胎儿体内致敏胎儿血小板后，使致敏血小板在网状内皮系统被巨噬细胞吞噬，从而导致患儿血小板减少，严重病例可发生颅内出血甚至胎死宫内。

Fetal and neonatal alloimmune thrombocytopenia (NAIT) is a blood disorder that affects pregnant women and their babies. NAIT was first reported in the literature in 1953 and is estimated to occur in as many as 1 in 1200 live births.

Neonatal alloimmune thrombocytopenia (NAITP, NAIT, NATP or NAT) is a disease that affects babies in which the platelet count is decreased because the mother's immune system attacks her fetus ' or newborn's platelets. A low platelet count increases the risk of …

FNAIT is a life threatening bleeding disorder that results from incompatibility between mother and baby for platelet-specific antigens. This may cause the maternal immune response to produce antibodies against platelet antigens that have been inherited paternally.

Fetal and neonatal alloimmune thrombocytopenia (FNAIT) is an alloimmune disorder resulting from platelet opsonization by maternal antibodies that destroy fetal platelets. The major risk of FNAIT is severe bleeding, particularly intracranial hemorrhage.

2022年7月12日 · Fetal and neonatal alloimmune thrombocytopenia (FNAIT) is a rare immune disorder. FNAIT occurs when the baby’s platelets are attacked and destroyed by the mother’s immune cells in her blood stream. This occurs when platelets from the baby are identified as foreign and the mother develops an antibody response against them.

2018年11月29日 · FNAIT is associated with severe bleeding, especially intracranial hemorrhage (ICH), in the fetus and/or newborn. More than 75% of ICHs occur in utero and up to 50% before 32 weeks gestation. The consequences of ICH include death (35%) or serious neurological sequelae in survivors (83%).

2021年2月23日 · 胎儿及新生儿同种免疫性血小板减少症（ fetal and neonatal alloimmune thrombocytopenia, FNAIT ）是由于胎儿与其母体血小板抗原不相容，来自母体的免疫球蛋白 G （ immunoglobulin G, IgG ）血小板抗体作用于胎儿血小板引起血小板破坏的同种免疫性疾病。