Ferroportin - Wikipedia
Given the findings of studies to date, there appears to be significant evidence that intact iron transport mechanisms are critical to normal neural tube closure. Furthermore, other …
Blood：研究揭示铁泵蛋白Fpn1在铁代谢中作用 - MedSci.cn
该论文以小鼠为实验模型，通过在巨噬细胞中条件性敲除铁泵蛋白Ferroportin1（Fpn1），首次阐明了巨噬细胞Fpn1在维持机体铁稳态的重要作用，揭示了Fpn1—巨噬细胞—免疫应激间的体 …
756 生命科学 第34 § 月26 日。Zon团队[12] 使用定位克隆技术鉴定出导 致斑马鱼突变体低色素性贫血的基因并将其命名为 ferroportin，详细展示了FPN 蛋白外排细胞铁的重 要功能。Zon团队 …
Ferroportin downregulation promotes cell proliferation by …
2019年8月19日 · Our study links FPN1 transcriptional and post-transcriptional regulation with MM cell growth and survival, and validates the prognostic value of FPN1 and its utility as a novel …
Blood：解决铁代谢多年难题，王福俤团队发现铁泵蛋白FPN降解调 …
2021年5月2日 · 来源 | 铁死亡club 铁元素 不仅是血红蛋白、肌红蛋白合成的主要原料，也是多种氧化还原酶类的辅因子。 作为人体含量最多的必需微量元素，铁稳态代谢对维持生命健康至关 …
Ferroportin 1 - an overview | ScienceDirect Topics
Ferroportin 1 (FPN1) is the only iron exporter identified in mammalian cells and is expressed mainly on the basolateral membrane of duodenal enterocytes and the plasma membranes of …
Cdh5-mediated Fpn1 deletion exerts neuroprotective effects …
2023年2月25日 · Ferroportin 1 (FPN1), the only known cellular iron export protein, is found in brain microvascular endothelial cells (BMVECs) at the blood-brain barrier, and is considered …
Iron Export through the Transporter Ferroportin 1 Is Modulated …
2016年8月12日 · Ferroportin 1 (FPN1) is an iron export protein found in mammals. FPN1 is important for the export of iron across the basolateral membrane of absorptive enterocytes …
Ferroportin disease: pathogenesis, diagnosis and treatment
Ferroportin Disease (FD) is an autosomal dominant hereditary iron loading disorder associated with heterozygote mutations of the ferroportin-1 ( FPN ) gene. It represents one of the …
<br>NRF2/FPN1通路的激活通过调节铁稳态和铁死亡来减轻糖尿 …
Ferroportin1 (FPN1) 是唯一与铁释放相关的哺乳动物蛋白，因此在铁稳态中发挥着至关重要的作用，而核因子 E2 相关因子 2 (NRF2) 则控制 FPN1 的转录。 由于NRF2/FPN1通路可能在糖尿 …