2023年7月15日 · Recent advances show that human focal segmental glomerulosclerosis (FSGS) is a primary podocytopathy caused by podocyte-specific gene mutations including NPHS1, NPHS2, WT-1, LAMB2, CD2AP, TRPC6, ACTN4 and INF2.

Focal segmental glomerulosclerosis (FSGS) is a histologic pattern of injury defined by the presence of sclerosis in some (segmental) of certain glomeruli (focal). On electron microscopy, it is characterized by a variable degree of podocyte foot process effacement and gaps in the coverage of the glomerular basement membrane.

Focal segmental glomerulosclerosis (FSGS) is a histologic lesion defined by the presence of sclerosis in part of some glomeruli seen on light microscopy (LM), immunofluorescence (IF) or electron microscopy (EM) examination on a kidney biopsy sample [1].

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Focal segmental glomerulosclerosis (FSGS) is now the most common cause of idiopathic (or primary) nephrotic syndromeanalgesic nephropathy]), atheroembolic disease affecting the kidneys, obesity, HIV infection (see HIV-associated nephropathy), and disorders causing nephron loss (eg, reflux nephropathy, subtotal nephrectomy, renal dysgenesis [eg, ...

2024年11月6日 · Focal segmental glomerulosclerosis (FSGS), first described in 1957, is currently recognized as one of the most common causes of primary glomerular diseases...

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Focal segmental glomerulosclerosis (FSGS) is a type of kidney disease that scars the kidneys, causing them to lose functionality.