Frontotemporal dementia (FTD) is a group of related conditions resulting from the progressive degeneration of the temporal and frontal lobes of the brain. These areas of the brain play a significant role in decision-making, behavioral control, emotion and language. What Causes FTD?

The overall goal of ALLFTD is to prepare for treatment trials in FTLD by focusing on several major activities: Characterizing FTLD patients (including familial FTLD [f-FTLD] and sporadic FTLD [s-FTLD]) followed at expert centers who can potentially be available for treatment trials

The goal of this study is to support the development of FTLD therapies through a multi-site research consortium headquartered at UCSF. The study aims to determine the clinical, genetic, and biomarker profiles of FTLD syndromes where there is a strong correlation between clinical syndrome and underlying pathology (FTD-ALS, PSP and semantic ...

2025年2月11日 · This is a biomarker study designed to collect and analyze blood specimens from individuals carrying known familial frontotemporal lobar degeneration (f-FTLD) mutations compared to a control group of individuals without known f-FTLD mutations.

ALLFTD studies both sporadic and genetic forms of frontotemporal lobar degeneration (FTLD), including behavioral variant FTD (bvFTD), primary progressive aphasia (PPA; both semantic and agrammatic variants), corticobasal syndrome (CBS/CBD), and progressive supranuclear palsy (PSP); genetic forms of FTLD may be due to mutations in several ...

UCSF is home to one of the few centers in the country that specialize in research and diagnosis of frontotemporal dementia. We offer extensive assessments to correctly diagnose FTD, which may be mistaken for other conditions, as well as medications to minimize symptoms.

2024年5月27日 · Improving our understanding of FTLD-tau pathobiology by engaging a diverse transdisciplinary team of scientists. Our FTD Center Without Walls (CWOW) goal is to improve our understanding of the pathobiological mechanisms underlying FTLD-tau.

This proposal describes a plan to study frontotemporal lobar degeneration (FTLD) using the infrastructure established by the Alzheimer's Disease Neuroimaging Initiative (ADNI). FTLD is a common cause of dementia, especially in patients under …

2019年10月16日 · The National Institutes of Health has awarded a five-year, multi-investigator research grant expected to total more than $63 million to Mayo Clinic and UC San Francisco, to advance treatments for frontotemporal lobar degeneration (FTLD).

This is a biomarker study designed to collect and analyze blood specimens from individuals carrying known familial frontotemporal lobar degeneration (f-FTLD) mutations compared to a control group of individuals without known f-FTLD mutations.