Fumarase (or fumarate hydratase) is an enzyme (EC 4.2.1.2) that catalyzes the reversible hydration / dehydration of fumarate to malate. Fumarase comes in two forms: mitochondrial …

Fumarase is an enzyme of the tricarboxylic acid (TCA) cycle in mitochondria, but in recent years, it has emerged as a participant in the response to DNA double strand breaks (DSBs) in the …

Fumarase (EC 4.2.1.2) catalyzes the reversible dehydration of l-malate to fumaric acid. Fumarase plays a key role in the TCA cycle and is extensively distributed in microorganisms, plants, and …

Fumarate hydratase (FH; also known as fumarase) is an enzyme found in both the cytoplasm and mitochondria of all eukaryotes. In mitochondria, FH is involved in generating energy for the cell …

Fumarase deficiency also called fumaric aciduria or fumarate hydratase deficiency, is an inherited condition that primarily affects the nervous system, especially the brain 1. Affected infants may …

Fumarase deficiency is a rare genetic disorder affecting the body's metabolism. This condition disrupts a specific enzyme responsible for energy production. It can lead to various health …

2010年3月9日 · In eukaryotes, fumarase (FH in human) is a well-known tricarboxylic-acid-cycle enzyme in the mitochondrial matrix. However, conserved from yeast to humans is a cytosolic …

Here we describe and discuss these fumarase related phenomena and in addition point out approaches for studying dual function of distributed proteins, in particular compartment …

The enzyme fumarase catalyzes the reversible hydration of fumarate to malate. The reaction catalyzed by fumarase is critical for cellular energetics as a part of the tricarboxylic acid cycle, …

2017年11月15日 · Living cells make an enzyme called fumarase. It converts a chemical called fumaric acid into L-malic acid. This is a crucial step in primary metabolism and aerobic …