2024年12月25日 · GATA1 (GATA Binding Protein 1) is a Protein Coding gene. Diseases associated with GATA1 include Thrombocytopenia With Beta-Thalassemia, X-Linked and …

The human GATA1 gene is located on the short (i.e. "p") arm of the X chromosome at position 11.23. It is 7.74 kilobases in length, consists of 6 exons, and codes for a full-length protein, …

该蛋白通过调节胎儿血红蛋白向成人血红蛋白的转换，在红细胞发育中发挥重要作用。 该基因的突变与 X 连锁红细胞生成异常性贫血和血小板减少症有关。 [RefSeq 提供，2008 年 7 月] This …

GATA1, also known as NF-E1, NF-1, Ery-1 and GF-1, is the founding member of the GATA family of transcription factors. It was first identified as a protein with binding specificity to the β -globin …

GATA1 is an essential downstream target of SENP1 and that the differential expression and response of GATA1 and Bcl-xL are a key mechanism underlying chronic mountain sickness …

The GATA1 gene provides instructions for making a protein that attaches (binds) to specific regions of DNA and helps control the activity of many other genes. Learn about this gene and …

2017年4月13日 · GATA1 mutations commonly occur in utero as early as week 21 of gestation in hematopoietic progenitors with trisomy 21. The resulting TMD is initially polyclonal, with …

GATA1 is a prototypical lineage-restricted transcription factor that is central to the correct differentiation, proliferation and apoptosis of erythroid and megakaryocytic cells.

2025年1月4日 · Title: Multidimensional profiling reveals GATA1-modulated stage-specific chromatin states and functional associations during human erythropoiesis. Molecular basis of …

GATA1 is known to be essential for hematopoiesis, megakaryocyte and platelet development. In mouse, Gata1 is a downstream target of NKX2-5 and is negatively regulated by the …