Glioblastoma, IDH-wildtype | Radiology Reference Article - Radiopaedia.org
2024年12月29日 · Glioblastomas, now defined as IDH-wildtype tumors, are essentially tumors of adults, usually occurring after the age of 40 years with a peak incidence between 65 and 75 …
胶质母细胞瘤IDH突变型意味着什么？ - 知乎专栏
胶质母细胞瘤（GBM）是颅脑最常见的恶性胶质瘤，其在基因分子水平诊断上分两种，分为IDH野生型和IDH突变型，IDH突变即为为异柠檬酸脱氢酶突变，是在这种肿瘤中发现的最重要的遗 …
IDH mutation in glioma: molecular mechanisms and potential
2020年4月15日 · In glioma, IDH mutations are recognised in >80% of World Health Organisation (WHO) grade II/III cases. 7 In WHO grade IV glioblastoma (GBM), IDH mutations are also …
IDH野生型胶质母细胞瘤特点、治疗及预后 - 知乎
IDH野生型GBM有时也被称为“IDH野生型原发性胶质母细胞瘤”，以区别于IDH突变型GBM，后者是由低级IDH突变型星形细胞瘤引起的。 临床特点. GBM可以发生在任何年龄（包括新生儿和婴 …
Long-term survival with IDH wildtype glioblastoma: first results …
Data on 280 patients with glioblastoma, among them 189 with IDH wildtype tumours, are reported. In total, 139 of 189 patients (74.3%) had tumours with MGMT promoter methylation. Median …
MRI transformer deep learning and radiomics for predicting IDH …
4 天之前 · Agarwal, A. et al. Molecular GBM versus histopathological GBM: radiology-pathology-genetic correlation and the new WHO 2021 definition of glioblastoma. AJNR Am. J. …
Analysis of IDH and EGFR as biomarkers in glioblastoma …
2024年8月15日 · Grade IV gliomas, including Isocitrate dehydrogenase (IDH) wild-type GBM and IDH mutant astrocytoma, are among the most malignant primary CNS tumors. Among them, …
Integrative data analysis of MGMT methylation and IDH1 mutation …
2025年1月1日 · Tumor histology reveals a strong correlation between IDH1 mutations and specific GBM characteristics. Compared to IDH-wildtype GBM, tumors with IDH1 mutations …
INC科普•脑瘤连载|IDH野生型胶质母细胞瘤-INC国际神经外科医生 …
2020年4月13日 · IDH野生型GBM有时也被称为“IDH野生型原发性胶质母细胞瘤”，以区别于IDH突变型GBM，后者是由低级IDH突变型星形细胞瘤引起的。 临床特点. GBM可以发生在任何年 …
2024年5月4日 · GBM（ molGBM），最新的中枢神经系统肿瘤分类将 molGBM归为“IDH-wt GBM（WHO 4级）”[7]。分析 病理诊断为GBM病例的基因表达状态，对肿瘤的分 类与诊断及肿 …