2025年1月18日 · 琥珀酸半醛脱氢酶缺乏症 （英语：Succinic semialdehyde dehydrogenase deficiency） 可造成GHB在血液中累积，造成麻醉效果。 历史上，γ-羟基丁酸曾被用作常用 镇静剂，用于治疗 失眠 、 抑郁症 、 发作性嗜睡病 和 酗酒，也被用于提高运动员成绩 [2]。 它在美国属于限制使用药物，被称作 Xyrem （英语：Xyrem），由Jazz Pharmaceuticals公司销售 [3]，用于治疗与 发作性嗜睡病 患者的日间嗜睡症状。 该神经药物在许多地区被认定为 毒品 而禁用 [4] （ …

γ-Hydroxybutyric acid, also known as gamma-hydroxybutyric acid, GHB, or 4-hydroxybutanoic acid, is a naturally occurring neurotransmitter and a depressant drug. It is a precursor to GABA, glutamate, and glycine in certain brain areas. It acts on the GHB receptor and is a weak agonist at the GABA B receptor.

γ-羟基丁酸（4-hydroxybutyric acid，GHB）是一种含有羧基和羟基的有机化合物（短链羟基脂肪酸），分子式为C4H8O3，常见使用形式为无色无味的液体（纯品）或白色无味的粉末（钠盐）。

Gamma-Hydroxybutyric acid (GHB) is another name for the generic drug sodium oxybate. Xyrem® (which is sodium oxybate) is the trade name of the FDA-approved prescription medication.

Gamma-hydroxybutyrate / butyric acid, ambiguously called GHB, presents some unique challenges for analysis due in part to its acidity, high polarity, and high solubility in aqueous solution.

GHB or Gamma Hydroxybutyrate (C 4 H 8 O 3) is a central nervous system (CNS) depressant that is commonly referred to as a “club drug” or “date rape” drug. GHB is abused by teens and young adults at bars, parties, clubs and “raves” (all night dance parties), and is often placed in alcoholic beverages.

2021年1月8日 · Gamma-hydroxybutyrate (GHB) is a short-chain fatty acid present endogenously in the brain and used therapeutically for the treatment of narcolepsy, as sodium oxybate, and for alcohol abuse/withdrawal.

2024年9月18日 · γ-Hydroxybutyric acid (GHB) is a GABA B /GHB receptor agonist which naturally occurs in the human brain. As a pharmaceutical agent, GHB was first synthesized by Henri Laborit in 1960 and was soon recognized to have unique …

琥珀酸半醛脱氢酶缺乏症 （英语：Succinic semialdehyde dehydrogenase deficiency） 可造成GHB在血液中累积，造成麻醉效果。 历史上，γ-羟基丁酸曾被用作常用 镇静剂，用于治疗 失眠 、 抑郁症 、 发作性嗜睡病 和 酗酒，也被用于提高运动员成绩 [2]。 它在美国属于限制使用药物，被称作 Xyrem （英语：Xyrem），由Jazz Pharmaceuticals公司销售 [3]，用于治疗与 发作性嗜睡病 患者的日间嗜睡症状。 该神经药物在许多地区被认定为 毒品 而禁用 [4] （其在中国大陆是第 …

2024年11月2日 · GHB is a short-chain fatty acid which is derived from the catabolism of GABA. Accumulation of GHB is the hallmark of SSADH deficiency, which is a rare autosomal recessive disorder with pathological variants in the gene aldehyde dehydrogenase 5 family member A1 (ALDH5A1) variants .