2024年12月25日 · Size: 558 amino acids Molecular mass: 61398 Da Protein existence level: PE1 Quaternary structure: Homohexamer (By similarity). Interacts with HADH; this interaction …

GLUD1 (glutamate dehydrogenase 1) is a mitochondrial matrix enzyme, one of the family of glutamate dehydrogenases that are ubiquitous in life, with a key role in nitrogen and glutamate …

2025年2月9日 · Title: Oncogenic circTICRR suppresses autophagy via binding to HuR protein and stabilizing GLUD1 mRNA in cervical cancer. Cytosolic GDH1 degradation restricts protein …

Glutamate dehydrogenase1 supports HIF-1alpha stability to promote colorectal tumorigenesis under hypoxia. Mosaic GLUD1 Mutations Associated with Hyperinsulinism Hyperammonemia …

Monoclonal Antibody for studying GLUD1. Validated for IF, IHC, WB. Available in 2 sizes. Highly specific and rigorously validated in-house, Glutamate Dehydrogenase 1/2 (D9F7P) Rabbit …

2023年7月7日 · We found spatial and reversal learning deficits, as well as large-scale mPFC transcriptional changes in pathways associated with glutamate and GABA signaling, in stress …

2024年1月12日 · GLUD1 overexpression significantly inhibited HCC cells proliferation, migration, invasion and tumor growth both in vitro and in vivo, while GLUD1 knocking-down promoted …

2020年1月10日 · Our cryo-EM analysis revealed a Y-shaped GluD1 receptor tetramer with a three-layered arrangement of the ATD, LBD, and transmembrane (TM) domains. The ATD …

Soro-Arnáiz and Fitzgerald et al. leverage ex vivo and in vivo models to identify how Glud1 determines muscle stem cell (MuSC) fate by controlling mitochondrial glutamate levels and, in …

Summary: This gene encodes glutamate dehydrogenase, which is a mitochondrial matrix enzyme that catalyzes the oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. …