G protein-coupled receptor 50 is a protein which in humans is encoded by the GPR50 gene. [5][6][7] GPR50 is a member of the G protein-coupled receptor family of integral membrane proteins and is most closely related to the melatonin receptor. [6] . GPR50 is able to heterodimerize with both the MT 1 and MT 2 melatonin receptor subtypes.

2024年8月15日 · G protein coupled receptor 50 promotes self-renewal and neuronal differentiation of embryonic neural progenitor cells through regulation of notch and wnt/beta-catenin signalings.

2024年12月25日 · GPR50 (G Protein-Coupled Receptor 50) is a Protein Coding gene. Diseases associated with GPR50 include Pituitary Adenoma 2, Growth Hormone-Secreting and X-Linked Intellectual Disability-Psychosis-Macroorchidism Syndrome. Among its related pathways are Class A/1 (Rhodopsin-like receptors) and Eicosanoid ligand-binding receptors.

2021年4月4日 · GPR50 is the mammalian ortholog of Mel1c: evidence of rapid evolution in mammals. Dufourny L, et al. BMC Evol Biol, 2008 Apr 9. PMID 18400093, Free PMC Article. What's a GeneRIF? GPR50-Ctail cleavage and nuclear translocation: a new signal transduction mode for G protein-coupled receptors.

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Reservoir capacity: 50 fluid ounces/1.4L; 60 cubic inch (1L) external storage pocket; Hard EVA spine; High-flow Mesh/EVA back panel; 2-way adjustable sternum strap; 5 Hook-and-loop locations on straps and back panel totaling 38 square inches; View full details GPR50 FAQs.

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G-protein coupled receptor 50 (GPR50) is an orphan G-protein coupled receptor with high sequence homology to the melatonin receptors MT1 and MT2. While classified as a member of the melatonin receptor family and also known as melatonin-related receptor, GPR50 does not bind melatonin (1).

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5 天之前 · The GPR50 is claimed to tip the scales at 2.5 lb (1.1 kg) when empty and 5.75 lb (2.6 kg) when full