2024年12月25日 · GPR143 (G Protein-Coupled Receptor 143) is a Protein Coding gene. Diseases associated with GPR143 include Albinism, Ocular, Type I and Nystagmus 6, …

The GPR143 gene, also known as OA1, provides instructions for making a protein that is involved in the coloring (pigmentation) of the eyes and skin. This protein is made in the light-sensitive …

G-protein coupled receptor 143, also known as Ocular albinism type 1 (OA1) in humans, is a conserved integral membrane protein with seven transmembrane domains and similarities with …

In this review we will introduce G protein-coupled receptor 143 (GPR143), an enigmatic receptor in terms of classification within the GPCR superfamily and localization. GPR143 has not been …

L-DOPA Receptor GPR143 Functionally Couples with Adrenergic alpha1B Receptor at the Second Transmembrane Interface. GPR143 controls ESCRT-dependent exosome biogenesis …

Lee et al. find that GPR143, an atypical GPCR, controls the ESCRT-dependent exosome biogenesis pathway, which determines exosomal protein cargo composition. In cancer, …

2023年2月27日 · Here, we find that GPR143, an atypical GPCR, controls the endosomal sorting complex required for the transport (ESCRT)-dependent exosome biogenesis pathway. …

GPR143 knockdown inhibited melanoma cell proliferation, migration, and colony formation while promoting apoptosis. Conclusions: Our findings suggest that GPR143 serves as a novel …

关于 gpr143 Cytogenetic location: Xp22.2 Genomic coordinates (GRCh38): X:9,725,346-9,778,602 (from NCBI) This gene has 5 transcripts (splice variants), 201 orthologues and is …

2024年5月2日 · Clinical resource with information about GPR143, Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array., Nystagmus 6, …