2024年12月25日 · GRIN2B (Glutamate Ionotropic Receptor NMDA Type Subunit 2B) is a Protein Coding gene. Diseases associated with GRIN2B include Developmental And Epileptic …

Pathogenic variants (“mutations”) in the GRIN2B gene cause a spectrum of neurodevelopmental disorders that can include childhood-onset epilepsy, developmental delays, movement …

Welcome to the GRIN2B Foundation! Our goal is to offer support to the growing community of children diagnosed with alterations in their GRIN2B gene.

2018年5月31日 · GRIN2B-related neurodevelopmental disorder is characterized by mild to profound developmental delay / intellectual disability (DD/ID) in all affected individuals.

Individuals with GRIN2B -related neurodevelopmental disorder have mild to profound intellectual disability and delayed development of speech and motor skills, such as sitting and walking. …

Glutamate [NMDA] receptor subunit epsilon-2, also known as N-methyl D-aspartate receptor subtype 2B (NMDAR2B or NR2B), is a protein that in humans is encoded by the GRIN2B gene.

GRIN2B is a gene located on the short arm (called “p”) of the 12th chromosome at 12p13.1. It is one member of a family of 7 genes, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D, GRIN3A, …

GRIN2B-related neurodevelopmental disorder is a rare neurodevelopmental disorder that is characterized by developmental delays and intellectual disabilities of variable degrees, muscle …

The GRIN2B gene provides instructions for making a protein called GluN2B. This protein is found in nerve cells (neurons) in the brain, primarily during development before birth. The GluN2B …

Mutations in GRIN2A and GRIN2B encoding regulatory subunits of NMDA receptors cause variable neurodevelopmental phenotypes. Positive Allosteric Modulators of GluN2A …