2023年7月30日 · Gamma-aminobutyric acid (GABA) inhibitors, or GABA antagonists, are drugs that inhibit the action of GABA, the primary inhibitory neurotransmitter of the central nervous system. They predominantly work at the GABA receptor.

GABA receptor antagonists are drugs that inhibit the action of GABA. In general these drugs produce stimulant and convulsant effects, and are mainly used for counteracting overdoses of sedative drugs.

A GABA reuptake inhibitor (GRI) is a type of drug which acts as a reuptake inhibitor for the neurotransmitter gamma-Aminobutyric acid (GABA) by blocking the action of the gamma-Aminobutyric acid transporters (GATs).

Gamma-aminobutyric acid (GABA) is an inhibitory neurotransmitter in your brain, meaning it slows your brain’s functions. GABA is known for producing a calming effect.

Gamma-Aminobutyric acid (GABA) reuptake inhibitors are analogs of gamma-Aminobutyric acid that bind to gamma-aminobutyric acid transporters and inhibit GABA reuptake. This increases extracellular levels of GABA and enhances GABA mediated synaptic activity in the brain.

2023年7月24日 · GABA is the primary inhibitory neurotransmitter in the brain, and it is a major inhibitory neurotransmitter in the spinal cord. The insulin-producing beta-cells of the pancreas produce GABA. It functions to inhibit pancreatic alpha cells, stimulate beta-cell growth, and convert alpha-cells to beta cells.

It is essential for maintaining the balance between nerve cell excitation and nerve cell inhibition. GABA acts like a brake in a car and slows down nerve cells that are over-excited. Because it calms the nervous system, it is called an inhibitory neurotransmitter.