Growth/differentiation factor 5 is a protein that in humans is encoded by the GDF5 gene. [5] [6] [7] The protein encoded by this gene is closely related to the bone morphogenetic protein (BMP) …

2024年12月25日 · GDF5 (Growth Differentiation Factor 5) is a Protein Coding gene. Diseases associated with GDF5 include Brachydactyly, Type C and Brachydactyly, Type A2. Among its …

该基因的突变与肢端小节发育不良、短指畸形、软骨发育不良、多发性骨关节挛缩综合征、近端交感神经管发育不良和骨关节炎易感性有关。 [RefSeq 提供，2016 年 8 月] This gene encodes …

this study identified growth differentiation factor 5 (GDF5) was a direct target gene of miR-665 in nucleus pulposus cell and enforced expression of miR-665 decreased GDF5 expression. …

2020年1月13日 · Growth and Differentiation Factor 5 (GDF5) is a major risk locus for osteoarthritis (OA), the most common joint disease characterised by progressive loss of …

GDF-5 is essential for cartilage development and homeostasis, and GDF-5 deficiency is associated with osteoarthritis (OA). Specifically, GDF-5 has high binding affinity to BMPR-IB, …

2025年1月4日 · GDF5 single-nucleotide polymorphism rs143383 is associated with lumbar disc degeneration in Northern European women. Williams FM, et al. Arthritis Rheum, 2011 Mar. …

GDF5 is related to the Bone Morphogenetic Proteins, which are involved in diverse physiological functions, including the development of the nervous system, where they play roles in early …

Growth differentiation factor 5 (GDF5) is a member of the bone morphogenic protein (BMP) family and plays critical roles in organ development processes including bone, cartilage, ligament, …

2024年1月18日 · 生长分化因子5(gdf5)是一种属于tgf-β超家族的细胞因子，起源于人体中的gdf5基因。 它在胚胎发育、骨骼形成和关节发育中扮演着重要角色。 GDF5在骨骼系统中调控骨细 …