A positive indirect antiglobulin (Coombs) test (IAT) before a blood transfusion indicates that your blood plasma contains antibodies that have the potential to react with certain antigens on donor red blood cells (RBCs).

Anti-IgG reagents remain important tools for determining the presence or absence of IgG on human red blood cells. The reagent is used in the investigation of hemolytic disease of the newborn...

There are several methods for antibody detection and each technique has advantages and limitations. We compared the performance of the tube (polyethylene glycol-indirect antiglobulin test [PEG-IAT]) and gel test technique for antibody identification.

The purpose of the present study was to design an antibody screening test based on the gel technique, pooled cells, and plasma and to evaluate this test by comparison with a conventional spin-tube indirect antiglobulin test (IAT) combined with a two-stage papain technique.

2024年9月11日 · Serologic test used in all transfusion services and reference labs; also known as the “Indirect Coombs” test or the simple abbreviation, “IAT.” This test is done to detect antibody and/or complement coating red cells following incubation with serum or plasma in the laboratory (the Direct Antiglobulin Test detects the same thing, but the ...

The direct (DAT) and indirect antiglobulin tests (IAT) are one of the most important diagnostic tools used in the investigation of immune mediated disorders. Recently, transfusion laboratories have seen the introduction of column technology in the form of …

2000年2月1日 · We compared the performance of the tube (polyethylene glycol-indirect antiglobulin test [PEG-IAT]) and gel test technique for antibody identification. From January to May 1999, we performed...

Consider in: transfusion-dependent patients (eg. sickle cell), patients with multiple antibodies, before starting treatments, eg. Daratumumab. IBGRL receive samples from all over the World. eg. Bombay phenotype (with anti-H) BSH Guidelines for pre-transfusion compatibility procedures in blood transfusion laboratories (2002).

We aimed to evaluate whether a PEG-IAT method, modified for gel technique, could replace the two-stage enzyme meth-od for routine identification of red blood cell (RBC) antibodies. A total of 161 selected patient samples were analyzed with the two-stage enzyme tube technique and the PEG-IAT in gel techniques.

The purpose of the present study was to design an antibody screening test based on the gel technique, pooled cells, and plasma and to evaluate this test by comparison with a conventional spin‐tube indirect antiglobulin test (IAT) combined with a two‐stage papain technique.