An exon – EXpressed regiON - is any part of a gene that will form a part of the final mature RNA produced by that gene after introns have been removed by RNA splicing. The term exon refers to both the DNA sequence within a gene and to the corresponding sequence in RNA transcripts.

2 天之前 · An exon is a region of the genome that ends up within an mRNA molecule. Some exons are coding, in that they contain information for making a protein, whereas others are non-coding. Genes in the genome consist of exons and introns.

2017年8月6日 · An exon is a coding region of a gene that contains the information required to encode a protein. In eukaryotes, genes are made up of coding exons interspersed with non-coding introns. These introns are then removed to make a functioning messenger RNA (mRNA) that can be translated into a protein.

2023年4月12日 · Exons are genomic regions that are transcribed to RNA and retained after introns are spliced out. We clarify the definition of an exon, which is often misused as synonymous to “protein coding.” We demonstrate that only a fraction of exonic sequences are protein coding and highlight the importance of non-coding exonic regions.

2025年3月17日 · CRISPR-Cas9 gene editing has emerged as a powerful tool for functional exon studies, permitting precise modification of exon sequences to investigate their role in protein function. These techniques enhance exon research, refining genetic diagnoses, therapeutic strategies, and our broader understanding of molecular biology.

1 天前 · The seven species are displayed in a phylogenetic order with unscaled branch length. Exon and intron lengths are shown with a log 2 (length + 1) transformation. The X-axis is the number of exons/introns per gene. That means, the exon/intron lengths (Y-axis) are grouped within these genes (each group is a box) and displayed separately in the ...

2010年4月8日 · There are three known evolutionary mechanisms that could account for the appearance of an alternatively spliced exon: exon shuffling (a form of gene duplication), exonization of intronic...

We describe here a method for the coordinated analysis of exon and intron data by investigating their relationship within individual genes and across samples, while taking into account changes in both variability and expression level.

2022年1月1日 · Exons of a gene are joined covalently in functional mature mRNA (transcript). The transcript after splicing is exported to the cytoplasm for translation. Exons are present in the genes of all eukaryotic organisms but absent in the genome of prokaryotes.

2024年12月31日 · Using a pipeline that we recently developed we first generated human meta-exons by collapsing overlapping exons in each gene and analyzed RNA-seq data from ENCODE to classify all human meta-exons expressed in any given tissue into one of the five exon categories that we defined: FEs, HFEs, IEs, hybrid internal-last exons (HLE) and LEs (Figure ...