Knockout of germline factor DDX4 causes defects in cell proliferation and migration. (a) Cell number analysis shows reduced counts in DDX4 knockout cell lines (C1, C2, and C3) …

DDX4, a conserved germline factor and RNA helicase, increases small cell lung cancer cell survival by regulating DNA damage and immune response pathways and contributes to …

2017年7月11日 · DDX4, a Drosophila Vasa ortholog, is another conserved germline factor in metazoans. 7, 8 It is a DEAD box RNA helicase and is implicated in translational regulation of …

2024年7月23日 · Here, we show that the germline-specific RNA helicase DDX4 forms germ-granule-like cytoplasmic ribonucleoprotein granules in various human tumors, but not in …

Vasa/Ddx4, a faithful DEAD-box family germline marker highly conserved across metazoan species, harbors canonical DEAD-box motifs and typical intrinsically disordered sequences at …

DDX4 (the human ortholog of Drosophila Vasa) is an RNA helicase and is present in the germ lines of all metazoans tested. It was historically thought to be expressed specifically in …

Here, we show that the germline-specific RNA helicase DDX4 forms germ-granule-like cytoplasmic ribonucleoprotein granules in various human tumors, but not in cultured can-cer …

2023年1月18日 · DDX4, a conserved germline factor and RNA helicase, increases small cell lung cancer cell survival by regulating DNA damage and immune response pathways and …

DDX4 is consistently localized with the mitotic apparatus in various blood-derived cancer cell lines and has essential roles in cell proliferation and migration – the functionalities for

2024年12月24日 · DDX4 (DEAD-Box Helicase 4) is a Protein Coding gene. Diseases associated with DDX4 include Infertility and Male Infertility. Among its related pathways are Signaling by …