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Gamma-glutamyl hydrolase - Wikipedia
In humans, gamma-glutamyl hydrolase is encoded by the GGH gene. [7][9][10] This gene catalyzes the hydrolysis of folylpoly-gamma-glutamates and antifolylpoly-gamma-glutamates by the removal of gamma-linked polyglutamates and glutamate. [10]
GGH Gene - GeneCards | GGH Protein | GGH Antibody
Dec 25, 2024 · GGH (Gamma-Glutamyl Hydrolase) is a Protein Coding gene. Diseases associated with GGH include Tropical Sprue and Cutis Laxa, Autosomal Dominant 1 . Among its related pathways are Innate Immune System and Fluoropyrimidine activity .
GGH | definition of GGH by Medical dictionary
ggh A gene on chromosome 8q12.3 that encodes gamma-glutamyl hydrolase, which progressively removes gamma-glutamyl residues from pteroyl poly-gamma-glutamate to yield pteroyl-alpha-glutamate (folic acid) and free glutamate.
8836 - Gene ResultGGH gamma-glutamyl hydrolase [ (human)]
GG genotype of GGH -354 T > G polymorphism may have high predictive value for myelosuppression in methotrexate treated rheumatoid arthritis patients. Suggest that GGH may serve as a potential biomarker of unfavorable clinical outcomes over short-term follow-up in …
Gamma-Glutamyl Hydrolase - an overview | ScienceDirect Topics
Gamma-glutamyl hydrolase (GGH) is a lysosomal enzyme involved in the metabolism of folates and anti-folates. It acts as an endo- and/or exo-peptidase to cleave gamma-polyglutamate chains that are attached to folates and anti-folates after they enter a mammalian cell.
GGH gamma-glutamyl hydrolase [ Homo sapiens (human) ]
Jan 4, 2025 · Title: High-Level γ-Glutamyl-Hydrolase (GGH) Expression is Linked to Poor Prognosis in ERG Negative Prostate Cancer. These results indicate that elevated expressions of the tumor-related genes FPGS/GGH and VEGF are correlated with malignancy of thymic carcinoma and B3 thymoma tumors.
GGH gamma-glutamyl hydrolase - NIH Genetic Testing Registry …
Feb 8, 2025 · Clinical resource with information about GGH, and available tests. There are links to practice guidelines and authoritative resources like GeneReviews, PubMed, MedlinePlus, PharmGKB and clinicaltrials.gov.
Gene GGH: Function, Expression, Mutations & Research
Learn about the GGH gene, including its function, expression, mutations, research, and potential implications for disease and therapy.
GGH Roofing
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