2015年10月1日 · A significant proportion of total circulating growth hormone (GH) is bound to a high affinity growth hormone binding protein (GHBP). Several low affinity binding proteins have …

Growth hormone-binding protein (GHBP) is a soluble carrier protein for growth hormone (GH). [1] The full range of functions of GHBP remains to be determined. [2] [3] However, current …

GHBP分为高亲和力的GHBP1和低亲和力的GHBP2两种，前者与GH的结合量占结合型的85%，血浆中的浓度约1mmol/L，是GH在血浆中的主要存在形式。 血液中的生长激素（GH）以结合型 …

2006年2月1日 · Circulating GH is partly bound to a high-affinity binding protein (GHBP), which in humans is derived from cleavage of the extracellular domain of the GH receptor. The precise …

Growth hormone-binding proteins are soluble extracellular or circulating proteins, structurally related to the extracellular hormone-binding domain of the growth hormone receptor, that bind …

GHBP binds about half of the circulating GH under basal conditions but is easily saturated at high GH levels; it subserves complex functions, including a circulating buffer/reservoir function for …

生长激素结合蛋白 (GHBP)被发现已有十余年,它来源于生长激素受体 (GHR)的细胞外成分,对人体的生长起着重要作用,对其研究可加深对GHR的认识,有助于更深入地阐明生长激素 (GH)的作 …

A soluble carrier growth hormone binding protein (GHBP) that can selectively and non-covalently interact with growth hormone, thereby acting as a modulator or inhibitor of growth hormone …

Circulating growth hormone binding proteins (GHBPs) have recently been recognized in a variety of species. Their discovery has added a new dimension to the physiology of growth hormone …

In the present review, we discuss various aspects that might affect differentially cellular GHR and circulating GHBP, based on species and tissue divergence, regulation of cell-surface GHR …