2023年3月20日 · Gigantism occurs when growth hormone hypersecretion occurs before the fusion of the long bone epiphysis and is characterized by tall stature. Acromegaly occurs when GH hypersecretion occurs after the fusion of the epiphysis leading to large extremities and characteristic facies.

2022年4月21日 · Gigantism and acromegaly are both caused by excess growth hormone. Gigantism, which develops during childhood, may be caused by a pituitary tumor or underlying condition.

Gigantism, also called pediatric acromegaly and pituitary gigantism, is a very rare condition that happens when a child or adolescent has high levels of growth hormone (GH) in their body, which causes them to grow very tall.

2024年1月18日 · Excess growth hormone causes both gigantism and acromegaly. The main difference between the two is that gigantism occurs in children before puberty, and acromegaly happens after puberty...

Gigantism and acromegaly are syndromes of excessive secretion of growth hormone (hypersomatotropism) that are nearly always due to a pituitary adenoma. Before closure of the epiphyses, the result is gigantism. Later, the result is acromegaly, which causes distinctive facial and other features.

Overproduction of growth hormone causes excessive growth. In children, the condition is called gigantism. In adults, it is called acromegaly. Excessive growth hormone is almost always caused by a noncancerous (benign) pituitary tumor. Children develop great stature, and adults develop deformed bones but do not grow taller.

Gigantism and acromegaly are patterns of abnormal growth caused by having too much growth hormone. In children, too much growth hormone causes gigantism, meaning being gigantic or a giant. In adults, too much growth hormone causes acromegaly. What causes gigantism and acromegaly? Gigantism and acromegaly are almost always caused by: