AMPA受体是由GluR1-4 (GluRA-D) 4个 亚基 组成的四异聚体，其形成起始于 粗面内质网 各个亚基的合成，每个亚基都有1个大的 N端 、3个 跨膜区域 、1个形成孔的 发夹结构 和1个位于胞质 …

In particular, several lines of evidence suggest that reversible phosphorylation of AMPAR subunit glutamate receptor 1 (GluR1, also referred to as GluA1 or GluR-A) plays a role in long-term …

GRIA1 (GluR1) is centrally involved in synaptic plasticity. Expression of the GluR1 gene is significantly reduced in the human frontal cortex with increasing age. [8]

在 大鼠 中通过 分子克隆技术，已发现5 种KA 受体亚型（GLUR5-7、KA-1、KA-2）,利用 逆转录PCR 及 膜片钳技术 揭示：KA 受体是由同类的不同 亚基 组成的异质组合体。 亚基的组成对受 …

AMPA 受体由四个序列高度同源且密切相关的基因组成。它们的相关产物 GluR1-GluR4 亚基以特定的比例和组合方式6 结合成四聚体，这决定了它们的通道功能。这些受体与许多其他细胞蛋 …

AMPARs are composed of four types of subunits encoded by different genes, designated as GRIA1 (also named GluA1 or GluR1), GRIA2 (also named GluA2 or GluR2), GRIA3 (Also …

囊泡膜谷氨酸转运体1（vesicular glutamate transporter 1， VGluT1）是兴奋性突触传递所必需的，谷氨酸需要转运到突触囊泡内并在大脑皮层内进行胞吐释放，故VGluT1的表达量不仅能够 …

2024年12月25日 · GRIA1 (Glutamate Ionotropic Receptor AMPA Type Subunit 1) is a Protein Coding gene. Diseases associated with GRIA1 include Intellectual Developmental Disorder, …

In particular, several lines of evidence suggest that reversible phosphorylation of AMPAR subunit glutamate receptor 1 (GluR1, also referred to as GluA1 or GluR-A) plays a role in long-term …

Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are …