GOG-33 - Free download as PDF File (.pdf), Text File (.txt) or read online for free. The document describes a study of surgical pathologic spread patterns of endometrial cancer. It involved 621 patients who underwent total hysterectomy and bilateral salpingo-oophorectomy with lymph node dissection and peritoneal cytology.

The overall rate of nodal metastasis is lower than reported in the original GOG 33. There was a sequential increase in the risk of lymph node metastases based on depth of uterine invasion, tumor grade, and the presence of lymphovascular space invasion.

2020年5月1日 · In GOG 33, which evaluated 621 patients with clinical stage 1 endometrial cancer, seven factors were significantly associated with pelvic and para-aortic nodal metastasis: grade, depth of myometrial invasion, peritoneal cytology, site of tumor location, adnexal involvement, other extrauterine metastases, LVSI, and histology [1].

1987年10月15日 · Paraaortic lymph node metastasis in endometrial cancer patients: a comprehensive analysis of rates, survival outcomes, and risk factors through systematic review and meta-analysis. Han L, Chen Y, Zheng A, Tan X, Chen H. Han L, et al. Front Oncol. 2024 Oct 31;14:1490347. doi: 10.3389/fonc.2024.1490347. eCollection 2024. Front Oncol. 2024.

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Gynecologic Oncology Group (GOG) 33, which was a prospective study of 621 women with disease clinically confined to the uterus who were treated with a total hysterectomy, BSO, pelvic and aortic LN dissection to the renal vessels and washings, helped identify risk factors for extrauterine spread in women with clinically stage I disease . On ...

In the Gynecologic Oncology Group (GOG) 33 study, Creasman et al. reported that 22% of patients with clinical stage I disease were upstaged after surgical staging due to extrauterine disease. Such a difference is associated with important prognostic and therapeutic implications, This led to the revision of the staging system for uterine cancer ...

GOG 33 was a large staging trial with nearly 1,200 pa-tients with endometrial cancer accrued between 1977 and 1983. Seventeen abstracts and publications resulted from this work along with numerous presentations.1-6 These findings led to the revision in FIGO surgical staging for endometrial cancer in 1988. The FIGO staging system

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