
GPM6A Gene - GeneCards | GPM6A Protein | GPM6A Antibody
2024年12月25日 · GPM6A (Glycoprotein M6A) is a Protein Coding gene. Diseases associated with GPM6A include Retinitis Pigmentosa 29 and Schizophrenia. Gene Ontology (GO) annotations related to this gene include calcium channel activity. An important paralog of this gene is GPM6B.
GPM6A - Wikipedia
Neuronal membrane glycoprotein M6-a is a protein that in humans is encoded by the GPM6A gene. [5] [6] [7]
Glycoprotein M6A (GPM6A) is a transmembrane protein on the surface of neurons in the central nervous system. This article reviews the vital roles of GPM6A in neuron development and synapse forming, and the relationship between GPM6A and neuropsychiatric disorders.
Neuronal Glycoprotein M6a: An Emerging Molecule in Chemical
2021年5月4日 · Neuronal glycoprotein M6a, encoded by the GPM6A gene is emerging as one of these molecules. M6a has been involved in neuron development and synapse formation and plasticity, and was also recently proposed as a gene-target in various neuropsychiatric disorders where it could also be used as a biomarker.
UniProt
GPM6A-induced filopodia formation involves mitogen-activated protein kinase (MAPK) and Src signaling pathways. May be involved in neuronal NGF-dependent Ca 2+ influx. May be involved in regulation of endocytosis and intracellular trafficking of G-protein-coupled receptors (GPCRs); enhances internalization and recycling of mu-type opioid ...
Zdhhc1- and Zdhhc2-mediated Gpm6a palmitoylation is essential …
2024年9月18日 · In this study, we identified Glycoprotein m6a (Gpm6a) as a critical protein for aMaSC activity modulation by using the Gpm6a knockout mouse model. Interestingly, we determined that Gpm6a depletion results in a reduction of Procr protein stability.
GPM6A glycoprotein M6A [ Homo sapiens (human) ] - National …
The yeast two-hybrid screen and the coimmunoprecipitation analysis identify the HIV-1 Nef interacting human protein glycoprotein M6A (GPM6A) in cells: PubMed
GPM6A glycoprotein M6A - NIH Genetic Testing Registry (GTR)
2025年1月4日 · Clinical resource with information about GPM6A, Biological insights from 108 schizophrenia-associated genetic loci., Common genetic variants associated with cognitive performance identified using the proxy-phenotype method., Genome-wide association study of temperament in bipolar disorder reveals significant associations with three novel Loci ...
糖蛋白 M6A(GPM6A)基因 | MCE - MCE-生物活性分子大师
Predicted to enable Calcium Channel activity. Involved in neuron migration and stem cell differentiation. Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022]
234267 - Gene ResultGpm6a glycoprotein m6a [ (house mouse)]
Gene ID: 234267, updated on 8-Feb-2025. Predicted to enable calcium channel activity. Involved in neural retina development and neuron projection morphogenesis. Acts upstream of or within response to bacterium. Located in axonal growth cone. Is expressed in central nervous system; intraembryonic coelom; metanephros; sensory organ; and upper lip.