2022年7月21日 · Gustatory Receptor 64 (Gr64) genes are a cluster of 6 neuronally expressed receptors involved in sweet taste sensation in Drosophila melanogaster. Gr64s modulate …

2015年3月2日 · Here, labellar sweet neurons of ΔGr64 mutant flies (lacking all six Gr64 genes) lost all spiking activity when stimulated with this sugar, similar to ΔGr5a mutants. This …

2008年11月25日 · The results with the Gr64f siRNA suggested that Gr64f might be the receptor that is required together with Gr5a to detect trehalose. This possibility was supported by a …

2022年12月19日 · To determine whether this local Hh source regulates sweet taste perception, we used Gr64f-Gal4 to express Hh-IR in mature sweet sensory neurons 38.

2025年2月20日 · One of the few identified sugar gustatory receptors identified so far and which promotes the starvation-induced increase of feeding motivation. Required in combination with …

(A) Expression of GFP in Gr64fGAL4 neurons reveals axon terminals in the sub-esophagael zone (SEZ). Scale bar = 50 μm. (B) Diagram of live-imaging experimental protocol. Cuticle above …

2022年3月28日 · Together, our studies have identified GR5a, GR61a, and Gr64f as novel sensors in the fly labellum, which allow for the detection of attractive amino acids in sweet-sensing …

2017年11月9日 · Previously, we showed that a broad population of sugar-sensing taste neurons expressing Gustatory Receptor 64f (Gr64f) is required for reflexive feeding responses to both …

Thus, the Gr64f- transgene provides a reliable tool to evaluate co-expres-GAL4 sion with the remaining Gr64LEXA alleles in sweet GRNs of the main taste organs (Figures 1B and S1).

2017年12月12日 · Behavioral studies have established that Drosophila appetitive taste responses towards fatty acids are mediated by sweet sensing Gustatory Receptor Neurons (GRNs). Here …